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Notice to Readers: 25th Anniversary of the Last Case of Naturally
Acquired Smallpox
On October 26, 1977, the last case of naturally acquired smallpox occurred in the Merca District of Somalia. In May
1980, the World Health Assembly certified the world free of naturally occurring smallpox. The eradication of a disease was
an unprecedented accomplishment. Eradication efforts for both paralytic poliomyelitis and dracunculiasis (i.e., guinea
worm disease) are ongoing. Beyond the benefit to the world population's health and economy, smallpox eradication
demonstrated the benefits of international commitment and cooperation toward a common cause in public health. Improvements made
in international vaccination programs, global disease surveillance, and public health logistics systems that were results of
the smallpox eradication program continue today
(1).
Although smallpox was eradicated in 1977, the risk for importation of disease into the United States had greatly
decreased before that time. As a result, the United States discontinued routine smallpox vaccinations for the general population in
1971, and the Advisory Committee on Immunization Practices recommended against routine vaccination of health-care workers
in 1976. The last case of smallpox in the United States occurred in 1949. An
MMWR report in 1997 commemorating the 20th anniversary of the eradication of smallpox noted that smallpox vaccine and its eradication of smallpox disease were on the
list of things that need be done only once in the history of the world
(1).
The U.S. public health system is preparing for the potential use of smallpox (variola) virus as a bioterrorism
agent. Although preparedness efforts have been ongoing since at least 1999 and a strategic plan for preparedness and
response against biologic and chemical terrorism was published in April 2000
(2), the terrorist attacks against the United States
on September 11, 2001, prompted extensive review of policies and procedures about potential acts of bioterrorism, especially
the intentional release of smallpox virus. To enhance preparedness, the U.S. Department of Health and Human Services
has contracted for production of enough smallpox vaccine for the entire U.S. population if vaccination becomes
necessary, developed a plan for responding to a smallpox attack (http://www.bt.cdc.gov/agent/smallpox/response-plan/index.asp), and
is reviewing whether increased vaccination before an attack is warranted and how such a vaccination program would
be
implemented. A final U.S. policy on smallpox vaccination is pending. Additional information on smallpox is available
at http://www.bt.cdc.gov/agent/smallpox/index.asp.
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Health and Human Services.References to non-CDC sites on the Internet are
provided as a service to MMWR readers and do not constitute or imply
endorsement of these organizations or their programs by CDC or the U.S.
Department of Health and Human Services. CDC is not responsible for the content
of pages found at these sites. URL addresses listed in MMWR were current as of
the date of publication.
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