Registry of Toxic Effects of Chemical Substances (RTECS)
Cyclopentane
RTECS #
GY2390000CAS #
287-92-3Updated
September 201Molecular Weight
70.15Molecular Formula
C5H10Synonyms
Cyclopentane (ACGIH)Pentamethylene
Acute Toxicity Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
inhalation/mammal (species unspecified) | lowest published toxic concentration: 3440 mg/m3 | Lung, Thorax, or Respiration: Other changes Liver: Other changes | TOVEFN (4),34,2000 |
inhalation/mouse | lethal concentration (50 percent kill): 72 gm/m3 | Behavioral: Somnolence (general depressed activity) Behavioral: Convulsions or effect on seizure threshold | TOVEFN (4),33,2000 |
inhalation/mouse | Lowest published lethal concentration: 110000 mg/m3 | Behavioral: General anesthetic | VCVGH* -,81,1990 |
inhalation/rat | lethal concentration (50 percent kill): 106000 mg/m3 | Behavioral: Somnolence (general depressed activity) Behavioral: Convulsions or effect on seizure threshold | TOVEFN (4),34,2000 |
ocular/rabbit | lowest published toxic dose: 100 pph | Eye: Conjunctiva irritation | TOVEFN (4),34,2000 |
oral/mouse | lethal dose (50 percent kill): 12800 mg/kg | Behavioral: Somnolence (general depressed activity) Behavioral: Convulsions or effect on seizure threshold | TOVEFN (4),34,2000 |
oral/rat | lethal dose (50 percent kill): 11400 mg/kg | Behavioral: Somnolence (general depressed activity) Behavioral: Convulsions or effect on seizure threshold | TOVEFN (4),34,2000 |
Other Multiple Dose Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
oral/rat | lowest published toxic dose: 34200 mg/kg/30D- intermittent | Kidney, Ureter, and Bladder: Renal function tests depressed Blood: Other changes | TOVEFN (4),33,2000 |
oral/rat | lowest published toxic dose: 34200 mg/kg/30D- intermittent | Kidney, Ureter, and Bladder: Renal function tests depressed Blood: Changes in other cell count (unspecified) | TOVEFN (4),34,2000 |
Reviews
Organization | Standard | Reference |
---|---|---|
American Conference of Governmental Industrial Hygienists (ACGIH) | Threshold Limit Value-time-weighted average 600 ppm | DTLVS* TLV/BEI,2013 |
TOXICOLOGY REVIEW | MUREAV 539,77,2003 |
Standards and Regulations
NIOSH Documentation and Surveillance
Organization | Standard | Reference |
---|---|---|
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CYCLOPENTANE-air | 10H time-weighted average 600 ppm | NIOSH* DHHS #95-121,1995 |
National Occupational Hazard Survey 1974 | Hazard Code 82935; Number of Industries 77; Total Number of Facilities 8027; Number of Occupations 52; Total Number of Employees Exposed 74753 |
Status in Federal Agencies
Organization | Reference |
---|---|
EPA TSCA Section 8(b) CHEMICAL INVENTORY | |
EPA TSCA Section 8(d) unpublished health/safety studies | |
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001 |
- Page last reviewed:March 7, 2014
- Page last updated:February 6, 2017
- Content source:
- National Institute for Occupational Safety and Health (NIOSH) Education and Information Division