Registry of Toxic Effects of Chemical Substances (RTECS)
1,3-Cyclopentadiene
RTECS #
GY1000000CAS #
542-92-7Updated
September 201Molecular Weight
66.11Molecular Formula
C5H6Synonyms
CyclopentadieneCyclopentadiene (ACGIH:OSHA)
Pentole
Pyropentylene
R-Pentine
Acute Toxicity Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
inhalation/human | lowest published toxic concentration: 35 mg/m3 | Behavioral: Headache | VCVGH* -,91,1990 |
inhalation/human | lowest published toxic concentration: 360 mg/m3 | Lung, Thorax, or Respiration: Dyspnea | VCVGH* -,91,1990 |
inhalation/mouse | lowest published toxic concentration: 15000 mg/m3 | Behavioral: General anesthetic | VCVGH* -,91,1990 |
inhalation/mouse | lethal concentration (50 percent kill): 14 gm/m3 | Behavioral: Excitement Behavioral: Muscle contraction or spasticity Behavioral: Aggression | GTPZAB 9(12),13,1965 |
inhalation/mouse | lethal concentration (16 percent kill): 9200 mg/m3 | VCVGH* -,91,1990 | |
inhalation/mouse | lethal concentration (50 percent kill): 11600 mg/m3 | VCVGH* -,91,1990 | |
inhalation/mouse | lethal concentration (84 percent kill): 17000 mg/m3 | VCVGH* -,91,1990 | |
inhalation/rat | lethal concentration (16 percent kill): 29000 mg/m3 | VCVGH* -,91,1990 | |
inhalation/rat | lethal concentration (50 percent kill): 35900 mg/m3 | VCVGH* -,91,1990 | |
inhalation/rat | lethal concentration (84 percent kill): 44000 mg/m3 | VCVGH* -,91,1990 | |
inhalation/rat | lethal concentration (50 percent kill): 39 gm/m3 | Behavioral: Excitement Behavioral: Muscle contraction or spasticity Behavioral: Aggression | GTPZAB 9(12),13,1965 |
inhalation/rat | lowest published toxic concentration: 60000 mg/m3 | Behavioral: General anesthetic | VCVGH* -,91,1990 |
oral/mouse | lethal dose (50 percent kill): 800 mg/kg | TPKVAL 9,27,1967 | |
oral/rat | lethal dose (50 percent kill): 113 mg/kg | NTIS** OTS0535718 | |
skin/rabbit | lethal dose (50 percent kill): 430 mg/kg | NTIS** OTS0535718 |
Other Multiple Dose Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
inhalation/rat | lowest published toxic concentration: 350 mg/m3/4H/26W- intermittent | Blood: Normocytic anemia Blood: Changes in erythrocyte (RBC) count | GTPZAB 9(12),13,1965 |
Reviews
Organization | Standard | Reference |
---|---|---|
American Conference of Governmental Industrial Hygienists (ACGIH) | Threshold Limit Value-time-weighted average 75 ppm | DTLVS* TLV/BEI,2013 |
Standards and Regulations
Organization | Standard | Reference |
---|---|---|
Mine Safety and Health Administration (MSHA) STANDARD-air | time-weighted average 75 ppm (200 mg/m3) | DTLVS* 3,66,1971 |
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV; | ||
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV | ||
Occupational Exposure Limit-AUSTRALIA | time-weighted average 75 ppm (203 mg/m3), JUL2008 | |
Occupational Exposure Limit-AUSTRIA | MAK-TMW 75 ppm (200 mg/m3), 2007 | |
Occupational Exposure Limit-BELGIUM | time-weighted average 75 ppm (206 mg/m3), MAR2002 | |
Occupational Exposure Limit-DENMARK | time-weighted average 75 ppm (200 mg/m3), MAY2011 | |
Occupational Exposure Limit-FINLAND | time-weighted average 75 ppm (210 mg/m3), short term exposure limit 120 ppm (330 mg/m3), NOV2011 | |
Occupational Exposure Limit-FRANCE | VME 75 ppm (200 mg/m3), FEB2006 | |
Occupational Exposure Limit-HUNGARY | time-weighted average 200 mg/m3, SEP2000 | |
Occupational Exposure Limit-ICELAND | time-weighted average 75 ppm (200 mg/m3), NOV2011 | |
Occupational Exposure Limit-KOREA | time-weighted average 75 ppm (200 mg/m3), 2006 | |
Occupational Exposure Limit-MEXICO | time-weighted average 75 ppm (200 mg/m3);short term exposure limit 150 ppm (400 mg/m3), 2004 | |
Occupational Exposure Limit-NEW ZEALAND | time-weighted average 75 ppm (203 mg/m3), JAN2002 | |
Occupational Exposure Limit-NORWAY | time-weighted average 40 ppm (110 mg/m3), JAN1999 | |
Occupational Exposure Limit-PERU | time-weighted average 75 ppm (203 mg/m3), JUL2005 | |
Occupational Exposure Limit-POLAND | time-weighted average 200 mg/m3, JAN1999 | |
Occupational Exposure Limit-RUSSIA | short term exposure limit 5 mg/m3, JUN2003 | |
Occupational Exposure Limit-SWITZERLAND | MAK-week 75 ppm (200 mg/m3), JAN2011 | |
Occupational Exposure Limit-THE NETHERLANDS | MAC-TGG 200 mg/m3, 2003 | |
Occupational Exposure Limit-THE PHILIPPINES | time-weighted average 75 ppm (200 mg/m3), JAN1993 | |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) | 8H time-weighted average 75 ppm (200 mg/m3) | CFRGBR 29,1926.55,1994 |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) | 8H time-weighted average 75 ppm (200 mg/m3) | CFRGBR 41,50-204.50,1994 |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) | 8H time-weighted average 75 ppm (200 mg/m3) | CFRGBR 29,1910.1000,1994 |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) | 8H time-weighted average 75 ppm (200 mg/m3) | CFRGBR 29,1915.1000,1993 |
NIOSH Documentation and Surveillance
Organization | Standard | Reference |
---|---|---|
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CYCLOPENTADIENE-air | 10H time-weighted average 75 ppm | NIOSH* DHHS #92-100,1992 |
National Occupational Exposure Survey 1983 | Hazard Code 20065; Number of Industries 1; Total Number of Facilities 3; Number of Occupations 3; Total Number of Employees Exposed 51 | |
National Occupational Hazard Survey 1974 | Hazard Code 20065; Number of Industries 19; Total Number of Facilities 3138; Number of Occupations 26; Total Number of Employees Exposed 18381 |
Status in Federal Agencies
Organization | Reference |
---|---|
EPA TSCA Section 8(b) CHEMICAL INVENTORY | |
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001 | |
NIOSH Analytical Method, 1994: 1,3-Cyclopentadiene, 2523 |
- Page last reviewed:March 7, 2014
- Page last updated:February 6, 2017
- Content source:
- National Institute for Occupational Safety and Health (NIOSH) Education and Information Division