Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to page options Skip directly to site content

Registry of Toxic Effects of Chemical Substances (RTECS)

Oxygen difluoride

RTECS #

RS2100000

CAS #

7783-41-7

Updated

September 201

Molecular Weight

54.00

Molecular Formula

F2O

Synonyms

Fluorine monoxide
Fluorine oxide
Oxygen difluoride (ACGIH:OSHA)
Oxygen fluoride

Reproductive Effects Data and References

Route/OrganismDoseEffectReference
inhalation/rat 5 mg/m3 (multigenerations)Reproductive: Specific developmental abnormalities: Blood and lymphatic systems (including spleen and marrow)VCVN5* -,359,1989

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/cat Lowest published lethal concentration: 71 mg/m3/2HPeripheral Nerve and Sensation: Spastic paralysis with/without sensory change

Lung, Thorax, or Respiration: Fibrosis, focal (pneumoconiosis)

Lung, Thorax, or Respiration: Acute pulmonary edema		STGNBT -,232,1999
inhalation/Dog lethal concentration (50 percent kill): 26 ppm/1HLung, Thorax, or Respiration: Acute pulmonary edema

Lung, Thorax, or Respiration: Other changes		AMRL** TR-70-77,1970
inhalation/human lowest published toxic concentration: 500 ppbLung, Thorax, or Respiration: Chronic pulmonary edema or congestion34ZIAG -,444,1969
inhalation/mammal (species unspecified) lethal concentration (50 percent kill): 480 mg/m3/5MVCVN5* -,359,1989
inhalation/monkey lethal concentration (50 percent kill): 26 ppm/1HBehavioral: Muscle weakness

Lung, Thorax, or Respiration: Chronic pulmonary edema or congestion

Gastrointestinal: Nausea or vomiting		AMRL** TR-70-77,1970
inhalation/mouse lethal concentration (50 percent kill): 1500 ppb/1HLung, Thorax, or Respiration: Acute pulmonary edema

Lung, Thorax, or Respiration: Other changes		AMRL** TR-70-77,1970
inhalation/rat lethal concentration (50 percent kill): 2600 ppb/1HLung, Thorax, or Respiration: Acute pulmonary edema

Lung, Thorax, or Respiration: Other changes		AMRL** TR-70-77,1970

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-ceiling concentration 0.05 ppmDTLVS* TLV/BEI,2013

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 0.05 ppm (0.1 mg/m3)DTLVS* 3,193,1971
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-ARAB Republic of Egypttime-weighted average 0.05 ppm (0.1 mg/m3), JAN1993
Occupational Exposure Limit-AUSTRALIAceiling concentration 0.05 ppm (0.11 mg/m3), JUL2008
Occupational Exposure Limit-AUSTRALIAtime-weighted average 2.5 mg(F)/m3, JUL2008
Occupational Exposure Limit-BELGIUMshort term exposure limit 0.05 ppm (0.11 mg/m3), MAR2002
Occupational Exposure Limit-DENMARKceiling concentration 0.05 ppm (0.1 mg/m3), MAY2011
Occupational Exposure Limit-FINLANDshort term exposure limit 0.05 ppm (0.11 mg/m3), NOV2011
Occupational Exposure Limit-ICELANDshort term exposure limit 0.05 ppm (0.1 mg/m3), NOV2011
Occupational Exposure Limit-KOREAceiling concentration 0.05 ppm (0.1 mg/m3), 2006
Occupational Exposure Limit-MEXICOpeak 0.05 ppm (0.1 mg/m3), 2004
Occupational Exposure Limit-MEXICOtime-weighted average 2.5 mg(F)/m3, 2004
Occupational Exposure Limit-NEW ZEALANDceiling concentration 0.05 ppm (0.11 mg/m3), JAN2002
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 2.5 mg(F)/m3, JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 0.05 ppm (0.1 mg/m3), JAN1999
Occupational Exposure Limit-PERUshort term exposure limit 0.05 ppm (0.11 mg/m3), JUL2005
Occupational Exposure Limit-POLANDMAC(time-weighted average) 1 mg(HF)/m3, MAC(short term exposure limit) 3 mg(HF)/m3, JAN1999
Occupational Exposure Limit-SWITZERLANDMAK-week 0.05 ppm (0.1 mg/m3), JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-C 0.1 mg/m3, 2003
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 0.05 ppm (0.1 mg/m3), JAN1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 0.05 ppm (0.1 mg/m3)CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 0.05 ppm (0.1 mg/m3)CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 0.05 ppm (0.1 mg/m3)CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 0.05 ppm (0.1 mg/m3)CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO OXYGEN DIFLUORIDE-airceiling concentration 0.05 ppmNIOSH* DHHS #92-100,1992

Follow NIOSH

NIOSH Homepage

TOP