Registry of Toxic Effects of Chemical Substances (RTECS)
Phosphorus chloride
RTECS #
TH3675000CAS #
7719-12-2Updated
September 201Molecular Weight
137.32Molecular Formula
Cl3PSynonyms
Fosforo(tricloruro di) (Italian)Fosfortrichloride (Dutch)
Phosphine, trichloro-
Phosphore(trichlorure de) (French)
Phosphorous chloride
Phosphortrichlorid (German)
Phosphorus trichloride
Phosphorus trichloride (ACGIH:OSHA)
Trichlorophosphine
Trojchlorek fosforu (Polish)
Acute Toxicity Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
inhalation/cat | lowest published toxic concentration: 40 mg/m3/6H | Lung, Thorax, or Respiration: Cough Eye: Conjunctiva irritation | VCVN5* -,71,1993 |
inhalation/cat | lowest published toxic concentration: 10 mg/m3/1H | Lung, Thorax, or Respiration: Respiratory depression | VCVN5* -,71,1993 |
inhalation/cat | Lowest published lethal concentration: 500 mg/m3 | VCVN5* -,71,1993 | |
inhalation/guinea pig | lethal concentration (50 percent kill): 50 ppm/4H | Eye: Other eye effects Behavioral: Irritability Lung, Thorax, or Respiration: Dyspnea | AIHAAP 25,470,1964 |
inhalation/guinea pig | lethal concentration (50 percent kill): 63.5 mg/m3 | VCVN5* -,71,1993 | |
inhalation/rabbit | Lowest published lethal concentration: 3500 mg/m3 | VCVN5* -,71,1993 | |
inhalation/rat | lowest published toxic concentration: 0.005 gm/m3 | Skin: After systemic exposure: Dermatitis, irritative | TPKVAL 13,107,1973 |
inhalation/rat | Lowest published lethal concentration: 0.31 gm/m3 | TPKVAL 13,107,1973 | |
inhalation/rat | Lowest published lethal concentration: 0.14 gm/m3 | Eye: Lacrimation Eye: Corneal damage Behavioral: Somnolence (general depressed activity) | TPKVAL 13,107,1973 |
inhalation/rat | lethal concentration (50 percent kill): 104 ppm/4H | Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi Lung, Thorax, or Respiration: Other changes Blood: Hemorrhage | AIHAAP 25,470,1964 |
inhalation/rat | lethal concentration (50 percent kill): 132 mg/m3 | VCVN5* -,71,1993 | |
ocular/rabbit | lowest published toxic dose: 100 pph | Lung, Thorax, or Respiration: Respiratory stimulation | TPKVAL 13,107,1973 |
oral/mammal (species unspecified) | lethal dose (50 percent kill): 350 mg/kg | GISAAA 39(4),86,1974 | |
oral/rat | lowest published lethal dose: 675 mg/kg | TPKVAL 13,107,1973 | |
oral/rat | lethal dose (50 percent kill): 18 mg/kg | Behavioral: Food intake (animal) Lung, Thorax, or Respiration: Chronic pulmonary edema or congestion Gastrointestinal: Peritonitis | ATDAEI 1,71,1990 |
oral/rat | lethal dose (16 percent kill): 430 mg/kg | Lung, Thorax, or Respiration: Respiratory depression Gastrointestinal: Ulceration or bleeding from stomach Liver: Other changes | TPKVAL 13,107,1973 |
oral/rat | lethal dose (50 percent kill): 550 mg/kg | TPKVAL 13,107,1973 | |
skin/mouse | lowest published toxic dose: 100 pph/5M | TPKVAL 13,107,1973 | |
skin/rabbit | lowest published lethal dose: 1260 mg/kg | Behavioral: Muscle weakness Liver: Change in gall bladder structure or function Blood: Other changes | ATDAEI 1,71,1990 |
Reviews
Organization | Standard | Reference |
---|---|---|
American Conference of Governmental Industrial Hygienists (ACGIH) | Threshold Limit Value-time-weighted average 0.2 ppm;short term exposure limit 0.5 ppm | DTLVS* TLV/BEI,2013 |
TOXICOLOGY REVIEW | FCTOD7 47,1287,2009 |
Standards and Regulations
Organization | Standard | Reference |
---|---|---|
Mine Safety and Health Administration (MSHA) STANDARD-air | time-weighted average 0.5 ppm (3 mg/m3) | DTLVS* 3,211,1971 |
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV; | ||
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV | ||
Occupational Exposure Limit-ARAB Republic of Egypt | time-weighted average 0.5 ppm (3 mg/m3), JAN1993 | |
Occupational Exposure Limit-AUSTRALIA | time-weighted average 0.2 ppm (1.1 mg/m3), short term exposure limit 0.5 ppm (2.8 mg/m3), JUL2008 | |
Occupational Exposure Limit-AUSTRIA | MAK-TMW 0.25 ppm (1.5 mg/m3);KZW 0.5 ppm (3 mg/m3), 2007 | |
Occupational Exposure Limit-BELGIUM | time-weighted average 0.2 ppm(1.1 mg/m3), short term exposure limit 0.5 ppm(2.8 mg/m3), MAR2002 | |
Occupational Exposure Limit-DENMARK | time-weighted average 0.2 ppm (1.2 mg/m3), MAY2011 | |
Occupational Exposure Limit-FINLAND | short term exposure limit 0.5 ppm (2.8 mg/m3), NOV2011 | |
Occupational Exposure Limit-FRANCE | VME 0.2 ppm (1.5 mg/m3), FEB2006 | |
Occupational Exposure Limit-GERMANY | MAK 0.5 ppm (2.8 mg/m3), 2011 | |
Occupational Exposure Limit-HUNGARY | time-weighted average 3 mg/m3, short term exposure limit 3 mg/m3, SEP2000 | |
Occupational Exposure Limit-ICELAND | time-weighted average 0.2 ppm (1.2 mg/m3), NOV2011 | |
Occupational Exposure Limit-JAPAN | Occupational Exposure Limit 0.2 ppm (1.1 mg/m3), MAY2012 | |
Occupational Exposure Limit-KOREA | time-weighted average 0.2 ppm (1.5 mg/m3), short term exposure limit 0.5 ppm (3 mg/m3), 2006 | |
Occupational Exposure Limit-MEXICO | time-weighted average 0.2 ppm (1.1 mg/m3), 2004 | |
Occupational Exposure Limit-MEXICO | time-weighted average 0.5 ppm (2.8 mg/m3), 2004 | |
Occupational Exposure Limit-NEW ZEALAND | time-weighted average 0.2 ppm (1.1 mg/m3), short term exposure limit 0.5 ppm (2.8 mg/m3), JAN2002 | |
Occupational Exposure Limit-NORWAY | time-weighted average 0.2 ppm (1.5 mg/m3), JAN1999 | |
Occupational Exposure Limit-PERU | time-weighted average 0,2 ppm (1,1 mg/m3); short term exposure limit 0,5 ppm (2,8 mg/m3), JUL2005 | |
Occupational Exposure Limit-POLAND | MAC(time-weighted average) 3 mg/m3, JAN1999 | |
Occupational Exposure Limit-RUSSIA | short term exposure limit 0.2 mg/m3, Skin, JUN2003 | |
Occupational Exposure Limit-SWEDEN | time-weighted average 0.2 ppm (1.2 mg/m3);short term exposure limit 0.4 ppm (2.4 mg/m3), JUN2005 | |
Occupational Exposure Limit-SWITZERLAND | ceiling concentration 0.25 ppm (1.5 mg/m3), JAN2011 | |
Occupational Exposure Limit-THE NETHERLANDS | MAC-TGG 1.5 mg/m3, 2003 | |
Occupational Exposure Limit-THE PHILIPPINES | time-weighted average 0.5 ppm (3 mg/m3), JAN1993 | |
Occupational Exposure Limit-TURKEY | time-weighted average 0.5 ppm (3 mg/m3), JAN1993 | |
Occupational Exposure Limit-UNITED KINGDOM | time-weighted average 0.2 ppm (1.1 mg/m3);short term exposure limit 0.5 ppm (2.9 mg/m3), OCT2007 | |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) | 8H time-weighted average 0.5 ppm (3 mg/m3) | CFRGBR 29,1926.55,1994 |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) | 8H time-weighted average 0.5 ppm (3 mg/m3) | CFRGBR 41,50-204.50,1994 |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) | 8H time-weighted average 0.5 ppm (3 mg/m3) | CFRGBR 29,1910.1000,1994 |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) | 8H time-weighted average 0.5 ppm (3 mg/m3) | CFRGBR 29,1915.1000,1993 |
NIOSH Documentation and Surveillance
Organization | Standard | Reference |
---|---|---|
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO PHOSPHORUS TRICHLORIDE-air | 10H time-weighted average 0.2 ppm;short term exposure limit 0.5 ppm | NIOSH* DHHS #92-100,1992 |
National Occupational Exposure Survey 1983 | Hazard Code 59166; Number of Industries 4; Total Number of Facilities 96; Number of Occupations 6; Total Number of Employees Exposed 2963; Total Number of Female Employees Exposed 329 | |
National Occupational Hazard Survey 1974 | Hazard Code 59166; Number of Industries 4; Total Number of Facilities 149; Number of Occupations 12; Total Number of Employees Exposed 2520 |
Status in Federal Agencies
- Page last reviewed:March 7, 2014
- Page last updated:February 6, 2017
- Content source:
- National Institute for Occupational Safety and Health (NIOSH) Education and Information Division