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Registry of Toxic Effects of Chemical Substances (RTECS)

Stoddard solvent

RTECS #

WJ8925000

CAS #

8052-41-3

Updated

September 201

Molecular Weight

N/R

Molecular Formula

N/R

Synonyms

Naphtha, solvent
Organic solvents, Stoddard solvent
Petroleum distillate fractions
Solvents, naphthas
Stoddard solvent (ACGIH:OSHA)
White spirits

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /human 100 ppm mildENTOX* -,100,2005
eye /rabbit 500 mg/24H moderateATDAEI 1,32,1990

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/cat Lowest published lethal concentration: 1700 ppm/7HBehavioral: Tremor

Behavioral: Convulsions or effect on seizure threshold		TXAPA9 32,282,1975
inhalation/Dog Lethal concentration: >8 gm/m3/8H-continuousBehavioral: Tremor

Behavioral: Convulsions or effect on seizure threshold		TXAPA9 32,282,1975
inhalation/Dog Lowest published lethal concentration: 8000 mg/m3/3HBehavioral: Alteration of classical conditioningVCVPS* -,80,1998
inhalation/rat lethal concentration (50 percent kill): >1400 ppm/8HENTOX* ,100,2005
inhalation/rat Lowest published lethal concentration: 8200 mg/m3/8HBehavioral: TremorVCVPS* -,80,1998
inhalation/rat Lethal concentration: >5500 mg/m3/4HBehavioral: Somnolence (general depressed activity)ATDAEI 1,32,1990
oral/rat Lethal dose: >5 gm/kgBehavioral: Somnolence (general depressed activity)ATDAEI 1,32,1990
skin/rabbit Lethal dose: >3 gm/kgATDAEI 1,32,1990

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/rat lowest published toxic concentration: 330 ppm/65D- intermittentKidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)

Blood: Other changes		TXAPA9 32,282,1975
inhalation/rat lowest published toxic concentration: 480 mg/m3/65D- intermittentBlood: Normocytic anemiaVCVPS* -,81,1998
inhalation/rat lowest published toxic concentration: 1100 mg/m3/65D- intermittentKidney, Ureter, and Bladder: Renal function tests depressed

Blood: Normocytic anemia		VCVPS* -,81,1998
skin/rabbit lowest published toxic dose: 2 gm/kg/4W- intermittentSkin: After systemic exposure: Dermatitis, otherNTIS** OTS0533989

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 100 ppmDTLVS* TLV/BEI,2013
TOXICOLOGY REVIEWTOLED5 128,85,2002
TOXICOLOGY REVIEWENTOX* -,100,2005
TOXICOLOGY REVIEWNTAPM* -,711,1995
TOXICOLOGY REVIEWNTAPM* -,727,1995
TOXICOLOGY REVIEWNTAPM* -,727,1995
TOXICOLOGY REVIEWNTAPM* -,747,1995
TOXICOLOGY REVIEWNTAPM* -,753,1995

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 790 mg/m3, JUL2008
Occupational Exposure Limit-BELGIUMtime-weighted average 100 ppm (533 mg/m3), MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 25 ppm (145 mg/m3), MAY2011
Occupational Exposure Limit-ICELANDtime-weighted average 25 ppm (145 mg/m3), skin, sen, NOV2011
Occupational Exposure Limit-KOREAtime-weighted average 100 ppm (525 mg/m3), 2006
Occupational Exposure Limit-MEXICOtime-weighted average 100 ppm (523 mg/m3);short term exposure limit 200 ppm (1050 mg/m3), 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 100 ppm (525 mg/m3), JAN2002
Occupational Exposure Limit-RUSSIAtime-weighted average 300 mg(C)/m3, short term exposure limit 900 mg(C)/m3, JUN2003
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 575 mg/m3, 2003
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 200 ppm (1150 mg/m3), JAN1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 200 ppm (1150 mg/m3)CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 500 ppm (2900 mg/m3)CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 500 ppm (2900 mg/m3)CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 200 ppm (1150 mg/m3)CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO STODDARD SOLVENT-airtime-weighted average 350 mg/m3;ceiling concentration 1800 mg/m3/15MNIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code 69855; Number of Industries 404; Total Number of Facilities 142653; Number of Occupations 222; Total Number of Employees Exposed 1922235; Total Number of Female Employees Exposed 230356
National Occupational Hazard Survey 1974Hazard Code 69855; Number of Industries 250; Total Number of Facilities 43857; Number of Occupations 135; Total Number of Employees Exposed 483167

Status in Federal Agencies

OrganizationReference
ATSDR TOXICOLOGY PROFILE (NTIS** PB/95/264263)
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Naphthas, 1550
OSHA ANALYTICAL METHOD #48

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