Vanadium fume

CAS number: 1314–62–1

NIOSH REL: 0.05 mg V/m³ 15-minute CEILING

Current OSHA PEL: 0.1 mg V₂O₅/m³ CEILING

1989 OSHA PEL: 0.05 mg V₂O₅/m³ CEILING

1993-1994 ACGIH TLV: 0.05 mg V₂O₅/m³ (respirable fume) TWA

Description of substance: Finely divided particulate dispersed in air.

LEL:. . Noncombustible Solid

Original (SCP) IDLH: 70 mg/m³ (as V₂O₅)

Basis for original (SCP) IDLH: The available data concerning the physiological effects of vanadium pentoxide (V₂O₅) refer either to V₂O₅ dust or just to V₂O₅, and do not specifically mention V₂O₅ fume. Patty [1963] stated that the lower limit for a V₂O₅ fume is based on the recognized greater toxicity of fume compared with dusts of larger particle size. Because no quantitative data are available specifically for V₂O₅ fume, the chosen IDLH is based on the report by ACGIH [1971] that 70 mg/m³ V₂O₅ dust is a lethal concentration for animals after a few hours of exposure [Hudson]. A margin of safety is present in the IDLH for the dust, because the exposure is for a few hours. Therefore, although based on an analogy with V₂O₅ dust, the IDLH for the fume is probably reasonable.

Short-term exposure guidelines: None developed

ACUTE TOXICITY DATA:

Animal data: It has been reported that 70 mg/m³ V₂O₅ dust is a lethal concentration after a few hours of exposure [Hudson].

Human data: None relevant for use in determining the revised IDLH.

Revised IDLH: 35 mg V/m3 Basis for revised IDLH: The revised IDLH for vanadium fume is 35 mg V/m3 based on an analogy to vanadium dust which has a revised IDLH of 35 mg V/m3.

REFERENCES:

1. ACGIH [1971]. Vanadium (as V). In: Documentation of the threshold limit values for substances in workroom air. 3rd ed. Cincinnati, OH: American Conference of Governmental Industrial Hygienists, pp. 275-276.

2. Hudson TGF [1964]. Vanadium, toxicology and biological significance. New York, NY: Elsevier Publishing Company, p. 75.

3. Patty FA, ed. [1963]. Industrial hygiene and toxicology. 2nd rev. ed. Vol. II. Toxicology. New York, NY: Interscience Publishers, Inc., p. 1182.