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NIOSH

BIS(2-CHLOROETHYL) ETHER

ICSC: 0417

Dichloroethyl ether
2,2'-Dichloroethyl ether
1,1'-Oxybis(2-chloro)ethane
sym-Dichloroethyl ether
Diethylene glycol dichloride
C4H8Cl2O / (ClCH2CH2)2O
Molecular mass: 143.02
ICSC # 0417 		CAS # 111-44-4
RTECS # KN0875000
UN # 1916
EC # 603-029-00-2
April 10, 2000 Validated

TYPES OF HAZARD/ EXPOSURE

ACUTE HAZARDS/ SYMPTOMS

PREVENTION

FIRST AID/
FIRE FIGHTING

FIRE Flammable. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames, NO sparks, and NO smoking.
Water spray, foam, powder, carbon dioxide.
EXPLOSION Above 55°C explosive vapour/air mixtures may be formed.
Above 55°C use a closed system, ventilation.
In case of fire: cool cylinder by spraying with water but avoid contact of the substance with water.
EXPOSURE
PREVENT GENERATION OF MISTS!

•INHALATION Cough. Sore throat. Nausea. Vomiting. Burning sensation. Laboured breathing. Symptoms may be delayed (see Notes).
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Half-upright position. Refer for medical attention.
•SKIN MAY BE ABSORBED!
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
•EYES Redness. Pain.
Face shield or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
•INGESTION Abdominal pain. Nausea. Vomiting. Burning sensation.
Do not eat, drink, or smoke during work. Wash hands before eating.
Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Rest. Refer for medical attention.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Ventilation. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Personal protection: chemical protection suit.
Fireproof. Separated from food and feedstuffs . See Chemical Dangers. Keep in the dark. Well closed.
Do not transport with food and feedstuffs.
Marine pollutant.
T+ symbol
R: 10-26/27/28-40
S: 1/2-7/9-27-28-36/37-45
UN Hazard Class: 6.1
UN Subsidiary Risks: 3
UN Packing Group: II
ICSC: 0417 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

BIS(2-CHLOROETHYL) ETHER

ICSC: 0417

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PHYSICAL STATE; APPEARANCE:
CLEAR, COLOURLESS LIQUID , WITH CHARACTERISTIC ODOUR.

PHYSICAL DANGERS:
The vapour is heavier than air.

CHEMICAL DANGERS:
The substance can form explosive peroxides on exposure to air and light. The substance decomposes on burning or on contact with water, producing toxic fumes including hydrogen chloride. Reacts with strong oxidants. Reacts violently with chlorosulfonic acid and oleum.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 5 ppm as TWA, 10 ppm as STEL; (skin); A4 (not classifiable as a human carcinogen); (ACGIH 2004).
MAK: 10 ppm, 59 mg/m3;
Peak limitation category: I(1);
skin absorption (H); (DFG 2004).
OSHA PEL†: TWA 15 ppm (90 mg/m3) skin
NIOSH REL: Ca TWA 5 ppm (30 mg/m3) ST 10 ppm (60 mg/m3) skin See Appendix A
NIOSH IDLH: Ca 100 ppm See: 111444


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion.

INHALATION RISK:
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance irritates the eyes and the respiratory tract. Inhalation of vapour may cause lung oedema (see Notes). Exposure far above the OEL may result in death. The effects may be delayed. Medical observation is indicated.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Repeated or prolonged contact with skin may cause dermatitis.

PHYSICAL
PROPERTIES

Boiling point: 178°C
Melting point: -50°C
Relative density (water = 1): 1.22
Vapour pressure, kPa at 25°C: 0.206
Relative vapour density (air = 1): 4.9
Flash point: 55°C c.c.
Auto-ignition temperature: 369°C
Explosive limits, vol% in air: 2.7-?
Octanol/water partition coefficient as log Pow: 1.29

ENVIRONMENTAL
DATA


N O T E S

The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation is therefore essential. Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered. An added stabilizer or inhibitor can influence the toxicological properties of this substance, consult an expert. Check for peroxides prior to distillation; eliminate if found. DCEE, Chlorex are trade names. Card has been partly updated in October 2005. See sections Occupational Exposure Limits, EU classification, Emergency Response.
Transport Emergency Card: TEC (R)-61GTF1-II

NFPA Code: H3; F2; R1;

ADDITIONAL INFORMATION



ICSC: 0417 BIS(2-CHLOROETHYL) ETHER
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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