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NIOSH

4-METHYLPYRIDINE

ICSC: 0803

4-Picoline
gamma-picoline
p-Picoline
C6H7N / (C5H4N)CH3
Molecular mass: 93.1
ICSC # 0803 		CAS # 108-89-4
RTECS # UT5425000
UN # 2313
EC # 613-037-00-8
March 25, 1999 Validated

TYPES OF HAZARD/ EXPOSURE

ACUTE HAZARDS/ SYMPTOMS

PREVENTION

FIRST AID/
FIRE FIGHTING

FIRE Flammable. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames, NO sparks, and NO smoking.
Powder, alcohol-resistant foam, water spray, carbon dioxide.
EXPLOSION Above 57°C explosive vapour/air mixtures may be formed.
Above 57°C use a closed system, ventilation, and explosion-proof electrical equipment.
In case of fire: keep drums, etc., cool by spraying with water.
EXPOSURE
PREVENT GENERATION OF MISTS!

•INHALATION Burning sensation. Cough. Dizziness. Drowsiness. Headache. Nausea. Sore throat. Unconsciousness. Weakness.
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Refer for medical attention.
•SKIN MAY BE ABSORBED! Dry skin. Redness. Burning sensation. Pain. Blisters. (Further see Inhalation).
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.
•EYES Redness. Pain. Severe deep burns.
Face shield, or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
•INGESTION Abdominal pain. Burning sensation. Diarrhoea. Vomiting. (Further see Inhalation).
Do not eat, drink, or smoke during work.
Rinse mouth. Do NOT induce vomiting. Rest. Refer for medical attention.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Chemical protection suit including self-contained breathing apparatus.
Fireproof. Separated from strong oxidants. Well closed.

Marine pollutant.
T symbol
R: 10-20/22-24-36/37/38
S: 1/2-26-36-45
UN Hazard Class: 3
UN Packing Group: III
ICSC: 0803 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

4-METHYLPYRIDINE

ICSC: 0803

I

M

P

O

R

T

A

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D

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A

PHYSICAL STATE; APPEARANCE:
COLOURLESS LIQUID , WITH CHARACTERISTIC ODOUR.

PHYSICAL DANGERS:


CHEMICAL DANGERS:
The substance decomposes on burning producing toxic fumes including nitrogen oxides. Reacts with oxidants.

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation through the skin and by ingestion.

INHALATION RISK:
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is corrosive to the eyes and the skin. The vapour of the substance irritates the respiratory tract. Exposure at high level may result in unconsciousness.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
The liquid defats the skin.

PHYSICAL
PROPERTIES

Boiling point: 144-145°C
Melting point: 3.7°C
Relative density (water = 1): 0.96
Solubility in water: miscible
Vapour pressure, kPa at 25°C: 0.76
Relative vapour density (air = 1): 3.2
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.02
Flash point: 57°C (o.c.)
Explosive limits, vol% in air: 1.3-8.7
Octanol/water partition coefficient as log Pow: 1.2

ENVIRONMENTAL
DATA


N O T E S

Also consult ICSC # 0801 (2-Methylpyridine) and 0802 (3-Methylpyridine).
Transport Emergency Card: TEC (R)-832/30G35.

NFPA Code: H 2; F 2; R 0.

ADDITIONAL INFORMATION



ICSC: 0803 4-METHYLPYRIDINE
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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