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L-ASPARTIC ACID

ICSC: 1439

L-Asparagic acid
(S)-Aminobutanedioic acid
L-Aminosuccinic acid
C4H7NO4
Molecular mass: 133.1
ICSC # 1439 		CAS # 56-84-8
RTECS # CI9098500
September 10, 2002 Validated
Ló, October 2001 (not reviewed); postponed in Montreal 2002 for more primary biological references.

TYPES OF HAZARD/ EXPOSURE

ACUTE HAZARDS/ SYMPTOMS

PREVENTION

FIRST AID/
FIRE FIGHTING

FIRE Combustible.
NO open flames.
In case of fire in the surroundings: use appropriate extinguishing media.
EXPLOSION Finely dispersed particles form explosive mixtures in air.
Prevent build-up of electrostatic charges (e.g., by grounding). Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting.

EXPOSURE
PREVENT DISPERSION OF DUST!

•INHALATION Cough. Sore throat.
Local exhaust or breathing protection.
Fresh air, rest. Refer for medical attention.
•SKIN
Protective gloves.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
•EYES Redness. Pain.
Safety spectacles.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
•INGESTION Bitter taste. Burning sensation in the throat and chest.
Do not eat, drink, or smoke during work.
Rinse mouth. Do NOT induce vomiting. Give plenty of water to drink.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water. (Extra personal protection: P1 filter respirator for inert particles.)
Separated from strong oxidants.

ICSC: 1439 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

L-ASPARTIC ACID

ICSC: 1439

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PHYSICAL STATE; APPEARANCE:
COLOURLESS CRYSTALS

PHYSICAL DANGERS:
Dust explosion possible if in powder or granular form, mixed with air. If dry, it can be charged electrostatically by swirling, pneumatic transport, pouring, etc.

CHEMICAL DANGERS:
The substance decomposes on burning producing toxic gases including nitrogen oxides . Reacts violently with oxidants.

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by ingestion.

INHALATION RISK:
Evaporation at 20°C is negligible; a nuisance-causing concentration of airborne particles can, however, be reached quickly when dispersed, especially, if powdered.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is irritating to the eyes and the respiratory tract .

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:

PHYSICAL
PROPERTIES

Decomposes below boiling point at 324°C
Melting point: 270°C
Density: 1.7
g/cm3
Solubility in water, g/100 ml: 0.45
Octanol/water partition coefficient as log Pow: -3.89

ENVIRONMENTAL
DATA


N O T E S

ADDITIONAL INFORMATION



ICSC: 1439 L-ASPARTIC ACID
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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