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NIOSH

RIBOFLAVIN

ICSC: 1454

Lactoflavine
Vitamin B2
C17H20N4O6
Molecular mass: 376.4
ICSC # 1454 		CAS # 83-88-5
RTECS # VJ1400000
October 10, 2002 Validated

TYPES OF HAZARD/ EXPOSURE

ACUTE HAZARDS/ SYMPTOMS

PREVENTION

FIRST AID/
FIRE FIGHTING

FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Coarse water spray, carbon dioxide.
EXPLOSION Finely dispersed particles form explosive mixtures in air.
Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting.

EXPOSURE
PREVENT DISPERSION OF DUST!

•INHALATION Cough. Sore throat.
Local exhaust or breathing protection.
Fresh air, rest.
•SKIN
Protective gloves.
Rinse and then wash skin with water and soap.
•EYES Redness. Pain.
Safety spectacles.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
•INGESTION
Do not eat, drink, or smoke during work.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Sweep spilled substance into covered containers; if appropriate, moisten first to prevent dusting.
Well closed.

ICSC: 1454 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

RIBOFLAVIN

ICSC: 1454

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PHYSICAL STATE; APPEARANCE:
ORANGE-YELLOW CRYSTALS

PHYSICAL DANGERS:
Dust explosion possible if in powder or granular form, mixed with air.

CHEMICAL DANGERS:
The substance decomposes on heating producing toxic fumes .

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by ingestion.

INHALATION RISK:
A nuisance-causing concentration of airborne particles can be reached quickly when dispersed.

EFFECTS OF SHORT-TERM EXPOSURE:


EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:

PHYSICAL
PROPERTIES

Melting point (decomposes): 280°C
Solubility in water, g/100 ml at 25°C: 0.01
Octanol/water partition coefficient as log Pow: -1.46

ENVIRONMENTAL
DATA


N O T E S

NFPA Code: H0; F3; R0;

ADDITIONAL INFORMATION



ICSC: 1454 RIBOFLAVIN
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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