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Tetrahydrofuran

Synonyms & Trade Names
Diethylene oxide, 1,4-Epoxybutane, Tetramethylene oxide, THF
CAS No.
109-99-9
RTECS No.
LU5950000
DOT ID & Guide
2056 127
Formula
C₄H₈O
Conversion
1 ppm = 2.95 mg/m3
IDLH
2000 ppm [10%LEL]
See: 109999
Exposure Limits
NIOSH REL
TWA 200 ppm (590 mg/m3) ST 250 ppm (735 mg/m3)
OSHA PEL
TWA 200 ppm (590 mg/m3) See Appendix G
Measurement Methods
NIOSH 1609 , 3800;
OSHA 7
See: NMAM or OSHA Methods
Physical Description
Colorless liquid with an ether-like odor.
Molecular Weight
72.1
Boiling Point
151°F
Freezing Point
-163°F
Solubility
Miscible
Vapor Pressure
132 mmHg
Ionization Potential
9.45 eV
Specific Gravity
0.89
Flash Point
6°F
Upper Exposive Limit
11.8%
Lower Explosive Limit
2%
Class IB Flammable Liquid: Fl.P. below 73°F and BP at or above 100°F.
Incompatibilities & Reactivities
Strong oxidizers, lithium-aluminum alloys [Note: Peroxides may accumulate upon prolonged storage in presence of air.]
Exposure Routes
inhalation, skin and/or eye contact, ingestion
Symptoms
irritation eyes, upper respiratory system; nausea, dizziness, headache, central nervous system depression
Target Organs
Eyes, respiratory system, central nervous system
Personal Protection/Sanitation
(See protection codes)
Skin:Prevent skin contact
Eyes:Prevent eye contact
Wash skin:When contaminated
Remove:When wet (flammable)
Change:No recommendation
First Aid
(See procedures)
Eye:Irrigate immediately
Skin:Water flush promptly
Breathing:Respiratory support
Swallow:Medical attention immediately
Respirator Recommendations

NIOSH/OSHA

Up to 2000 ppm:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode£
(APF = 50) Any chemical cartridge respirator with a full facepiece and organic vapor cartridge(s)
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
(APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s)£
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece

Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus

Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
Any appropriate escape-type, self-contained breathing apparatus

Important additional information about respirator selection

See also
INTRODUCTION   ICSC CARD: 0578

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