National Center for Advancing and Translational Sciences Genetic and Rare Diseases Information Center, a program of the National Center for Advancing and Translational Sciences

Paramyotonia congenita



I was diagnosed with paramyotonia congenita when I was young.  If I have children, would pregnancy cause serious health issues related to my condition?

There is limited information in the medical literature regarding the effects of pregnancy in individuals with paramyotonia congenita, as this condition is quite rare.  One article described the experience of four women with this condition: one experienced worsening of her symptoms during pregnancy, whereas three did not.[1]  Another article on paramyotonia congenita and related conditions listed pregnancy as a possible trigger of muscle weakness in affected women.[2]  Though there is little information about pregnancy in women with paramyotonia congenita, general information about women affected by other myotonia conditions suggests symptoms may worsen during pregnancy, but quickly return to usual levels after pregnancy.[3]
Last updated: 5/20/2012

We hope this information is helpful. We strongly recommend you discuss this information with your doctor. If you still have questions, please contact us.

Warm regards,
GARD Information Specialist

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  1. Wegmüller E, Ludin HP, Mumenthaler M. Paramyotonia congenita. A clinical, electrophysiological and histological study of 12 patients. Journal of Neurology. 1979; 220:251-257. http://www.ncbi.nlm.nih.gov/pubmed/90134. Accessed 5/18/2012.
  2. Finsterer J. Primary periodic paralyses. Acta Neurologica Scandinavica. 2008; 117:145-158. http://www.ncbi.nlm.nih.gov/pubmed/18031562. Accessed 5/18/2012.
  3. Argov Z, de Visser M. What we do not know about pregnancy in hereditary neuromuscular disorders. Neuromuscular Disorders. 2009; 19:675-679. http://www.ncbi.nlm.nih.gov/pubmed/19692244. Accessed 5/18/2012.