2-OH-NPA

2-OH-NPA
Identifiers
IUPAC name
  • (R)-2,10,11-Trihydroxy-N-propylnoraporphine
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC19H21NO3
Molar mass311.381 g·mol−1
3D model (JSmol)
SMILES
  • c4c3c2c(cc4O)-c1c(ccc(O)c1O)CC2N(CC3)CCC
InChI
  • InChI=1S/C19H21NO3.BrH/c1-2-6-20-7-5-12-8-13(21)10-14-17(12)15(20)9-11-3-4-16(22)19(23)18(11)14;/h3-4,8,10,15,21-23H,2,5-7,9H2,1H3;1H/t15-;/m1./s1 checkY
  • Key:KIAIFHTWTMKEDI-XFULWGLBSA-N checkY
  (verify)

2-OH-NPA is a drug used in scientific research which acts as a potent and selective agonist for the dopamine D2 receptor.[1]

References

  1. ↑ Gao YG, Baldessarini RJ, Kula NS, Neumeyer JL (June 1990). "Synthesis and dopamine receptor affinities of enantiomers of 2-substituted apomorphines and their N-n-propyl analogues". Journal of Medicinal Chemistry. 33 (6): 1800–1805. doi:10.1021/jm00168a040. PMID 1971309.
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