Carumonam

Carumonam
Clinical data
Trade namesAmasulin
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
IUPAC name
  • 2-[(Z)-[1-(2-Amino-1,3-thiazol-4-yl)-2-[[(2S,3S)-2-(carbamoyloxymethyl)-4-oxo-1-sulfoazetidin-3-yl]amino]-2-oxoethylidene]amino]oxyacetic acid
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC12H14N6O10S2
Molar mass466.40 g·mol−1
3D model (JSmol)
SMILES
  • C1=C(N=C(S1)N)/C(=N/OCC(=O)O)/C(=O)N[C@H]2[C@H](N(C2=O)S(=O)(=O)O)COC(=O)N
InChI
  • InChI=1S/C12H14N6O10S2/c13-11-15-4(3-29-11)7(17-28-2-6(19)20)9(21)16-8-5(1-27-12(14)23)18(10(8)22)30(24,25)26/h3,5,8H,1-2H2,(H2,13,15)(H2,14,23)(H,16,21)(H,19,20)(H,24,25,26)/b17-7-/t5-,8+/m1/s1 checkY
  • Key:UIMOJFJSJSIGLV-JNHMLNOCSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Carumonam (INN) is a monobactam antibiotic.[1] It is very resistant to beta-lactamases, which means that it is more difficult for bacteria to break down using β-lactamase enzymes.[2]

References

  1. ↑ McNulty CA, Garden GM, Ashby J, Wise R (September 1985). "Pharmacokinetics and tissue penetration of carumonam, a new synthetic monobactam". Antimicrobial Agents and Chemotherapy. 28 (3): 425–7. doi:10.1128/aac.28.3.425. PMC 180266. PMID 4073864.
  2. ↑ PubChem. "Carumonam". pubchem.ncbi.nlm.nih.gov. Retrieved 2021-12-08.
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