List of skin conditions associated with internal cancer

This is a list of skin conditions associated with internal cancer.[1][2] It does not include skin infections associated with cancer or cancers that spread to skin.[2] Some have stronger associations with cancers than others.[3]

Cutaneous conditions associated with internal benign tumors and/or malignancies
Cutaneous conditionInternal malignancyImageNotes
Acanthosis nigricans[3]
Acquired ichthyosis[4]Hodgkin disease
Acrokeratosis paraneoplasticaSquamous cell carcinoma of the upper respiratory or gastrointestinal tracts
Clubbing of fingers[3]Lung cancer[3]
DermatomyositisLung cancer in men, breast and gynaecological tumours in women and colorectal cancers in both sexes
Erythema gyratum repens[5]Lung cancer, breast cancer, oesophageal cancer
Erythroderma and exfoliative dermatitisMycosis fungoides or Sézary syndrome
Hypertrichosis lanuginosa acquisitaLung cancer
Leser–Trélat signGastrointestinal adenocarcinoma
Migratory thrombophlebitisPancreatic adenocarcinoma
Necrolytic migratory erythemaGlucagon secreting pancreatic islet cell adenoma
Paraneoplastic pemphigusNon-Hodgkin lymphoma[nb 1]
Chronic lymphocytic leukemia
Castleman's disease[nb 1]
Sarcoma
Thymoma
Paraneoplastic pigmentationSmall cell bronchial carcinoma
Pityriasis rotundaHepatocellular carcinoma
Porphyria cutanea tarda and variegate porphyriasHepatocellular Carcinoma
Pyoderma gangrenosumHematological malignancy
Scleroderma‐like skin changesCarcinoid syndrome
Sweet syndromeHematological malignancy
Tripe palms[3]Lung cancer, stomach cancer, ovarian cancer[3]
Trousseau sign of malignancy

Footnotes

  1. 1 2 Non-Hodgkin lymphoma is the most common cause of paraneoplastic pemphigus in adults. Castleman's disease is the most common cause of paraneoplastic pemphigus in children.

See also

References

  1. James, William D.; Elston, Dirk; Treat, James R.; Rosenbach, Misha A.; Neuhaus, Isaac (2020). "28. Dermal and subcutaneous tumors". Andrews' Diseases of the Skin: Clinical Dermatology (13th ed.). Edinburgh: Elsevier. pp. 633–634. ISBN 978-0-323-54753-6. Archived from the original on 2023-08-08. Retrieved 2023-08-07.
  2. 1 2 Wick, Mark R.; Patterson, James W. (July 2019). "Cutaneous paraneoplastic syndromes". Seminars in Diagnostic Pathology. 36 (4): 211–228. doi:10.1053/j.semdp.2019.01.001. ISSN 0740-2570. PMID 30736994. Archived from the original on 2022-11-21. Retrieved 2023-08-01.
  3. 1 2 3 4 5 6 Fonia, Athina; Baran, Robert (2021). "Cutaneous paraneoplastic syndromes with nail involvement". In Lipner, Shari (ed.). Nail Disorders: Diagnosis and Management, An Issue of Dermatologic Clinics. Elsevier. pp. 175–182. ISBN 978-0-323-70924-8. Archived from the original on 2023-08-02. Retrieved 2023-08-01.
  4. James, William D.; Elston, Dirk; Treat, James R.; Rosenbach, Misha A.; Neuhaus, Isaac (2020). "27. Genodermatoses and congenital anomalies". Andrews' Diseases of the Skin: Clinical Dermatology (13th ed.). Edinburgh: Elsevier. pp. 563–565. ISBN 978-0-323-54753-6. Archived from the original on 2023-08-05. Retrieved 2023-08-04.
  5. Bolognia, Jean L.; Schaffer, Julie V.; Duncan, Karynne O.; Ko, Christine (2021). "15. Figurate erythemas". Dermatology Essentials (2nd ed.). Elsevier. pp. 142–148. ISBN 978-0-323-70971-2. Archived from the original on 2023-08-08. Retrieved 2023-08-05.


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