Pamabrom

Pamabrom
Clinical data
AHFS/Drugs.com	Multum Consumer Information
MedlinePlus	a681004
ATC code	none;
Legal status
Legal status	US: OTC ;
Identifiers
	IUPAC name 1:1 mixture of 2-amino-2-methyl-1-propanol and 8-bromotheophyllinate;
CAS Number	606-04-2 ;
PubChem CID	11806;
ChemSpider	11313 ;
UNII	UA8U0KJM72;
ChEMBL	ChEMBL2104825 ;
CompTox Dashboard (EPA)	DTXSID80209397 ;
ECHA InfoCard	100.009.186
Chemical and physical data
Formula	8-Bromotheophylline: C7H7BrN4O2; 2-Amino-2-methyl-1-propanol: C4H11NO
Molar mass	348.20 g/mol
3D model (JSmol)	Interactive image;
	SMILES Cn2c(=O)c1[nH]c(Br)nc1n(C)c2=O.NC(C)(C)CO;
	InChI InChI=1S/C7H7BrN4O2.C4H11NO/c1-11-4-3(9-6(8)10-4)5(13)12(2)7(11)14;1-4(2,5)3-6/h1-2H3,(H,9,10);6H,3,5H2,1-2H3 ; Key:ATOTUUBRFJHZQG-UHFFFAOYSA-N ;
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Pamabrom (trade name Diurex Max) is manufactured by Jig Chemical, and is a product included in retail drugs available in over-the-counter medications. The active diuretic ingredient in pamabrom is 8-bromotheophylline and it also contains aminoisobutanol.

Pamabrom is available in combination with acetaminophen (paracetamol) for various conditions such as back pain and menstrual relief.^[1] The acetaminophen helps reduce menstrual pains and the pamabrom reduces associated bloating. The combination is available in a number of products from various brands under different names. The dosages are essentially the same for each brand, including generic drug store varieties.

A diuretic is also used to reduce fluid buildup in the body. When the body has fluid buildup, it can cause swelling of the extremities, like in your ankles and feet. Excess fluid can make it harder for your heart to work properly. Buildup of these fluids are sometimes related to congestive heart failure.

References

↑ Di Girolamo G, Sánchez AJ, De Los Santos AR, González CD (March 2004). "Is acetaminophen, and its combination with pamabrom, an effective therapeutic option in primary dysmenorrhoea?". Expert Opinion on Pharmacotherapy. 5 (3): 561–70. doi:10.1517/14656566.5.3.561. PMID 15013925.

External links

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[pmid15013925-1] Di Girolamo G, Sánchez AJ, De Los Santos AR, González CD (March 2004). "Is acetaminophen, and its combination with pamabrom, an effective therapeutic option in primary dysmenorrhoea?". Expert Opinion on Pharmacotherapy. 5 (3): 561–70. doi:10.1517/14656566.5.3.561. PMID 15013925.

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