Rafivirumab

Rafivirumab
Monoclonal antibody
Type	Whole antibody
Source	Human
Target	rabies virus glycoprotein
Clinical data
ATC code	none
Identifiers
CAS Number	944548-37-2^N
ChemSpider	none
UNII	F6G4126BPE
Chemical and physical data
Formula	C₆₄₆₂H₉₉₅₄N₁₇₁₈O₂₀₃₆S₄₆
Molar mass	145761.46 g·mol⁻¹
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Rafivirumab (CR57) is a monoclonal antibody for the prophylaxis of rabies.^[1]^[2]^[3]

References

↑ "International Nonproprietary Names for Pharmaceutical Substances (INN)" (PDF). World Health Organization.
↑ Kramer RA, Marissen WE, Goudsmit J, Visser TJ, Clijsters-Van der Horst M, Bakker AQ, et al. (July 2005). "The human antibody repertoire specific for rabies virus glycoprotein as selected from immune libraries". European Journal of Immunology. 35 (7): 2131–45. doi:10.1002/eji.200526134. PMID 15971273.
↑ Franka R, Carson WC, Ellison JA, Taylor ST, Smith TG, Kuzmina NA, et al. (September 2017). "In Vivo Efficacy of a Cocktail of Human Monoclonal Antibodies (CL184) Against Diverse North American Bat Rabies Virus Variants". Tropical Medicine and Infectious Disease. 2 (3): 48. doi:10.3390/tropicalmed2030048. PMC 6082099. PMID 30270905.

Monoclonal antibodies for infectious disease and toxins

Human	Efungumab^†

Human	Ansuvimab Atoltivimab (+maftivimab/odesivimab) Bamlanivimab^† (+etesevimab)^† Bebtelovimab^§ Casirivimab^† (+imdevimab) Cilgavimab^† (+tixagevimab)^† Diridavumab^§ Etesevimab^† Exbivirumab^§ Foravirumab^§ Imdevimab^† (+casirivimab) Libivirumab^§ Maftivimab Odesivimab Rafivirumab^§ Regavirumab^§ Regdanvimab Sevirumab^† Sotrovimab Suptavumab Tixagevimab^† (+cilgavimab)^† Tuvirumab^§ Nirsevimab^†
Chimeric	Cosfroviximab Larcaviximab Porgaviximab
Humanized	Felvizumab^§ Lenvervimab^† Motavizumab^† Palivizumab Suvizumab^§

Bacterial

Human	Nebacumab Panobacumab^§ Raxibacumab
Mouse	Edobacomab^§
Chimeric	Pagibaximab^†
Humanized	Tefibazumab^†

Human	Actoxumab^§ Bezlotoxumab Suvratoxumab
Chimeric	Obiltoxaximab
Humanized	Urtoxazumab^§

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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