Sebaceous adenoma

Sebaceous adenoma
Sebaceous adenoma in a person with Lynch syndrome
SpecialtyDermatology
SymptomsSolitary small bump on face and neck[1]
Risk factorsMuir-Torre syndrome[1]
Differential diagnosisSebaceous hyperplasia, sebaceoma[1]
PrognosisGood[1]

A sebaceous adenoma, is a noncancerous tumor of the skin.[1] It typically occurs as a single small well-defined yellowish bump in sun-damaged skin of usually the neck and face, of a person older than age 40 years.[1] On the rare chance that there is more than one, there is a possibility of Muir–Torre syndrome.[1]

Like sebaceous carcinoma and sebaceoma, it also has sebaceous differentiaton, and is mainly made up of completely differentiated sebocytes.[1]

Signs and symptoms

It typically occurs as a single well-defined small yellowish small bump in sun-damaged skin of usually the neck and face, of a person older than age 40 years.[1] On the rare chance that there is more than one, there is a possibility of Muir–Torre syndrome.[1]

Pathophysiology

  • Sebaceous adenoma reveals nuclear negativity for repair enzyme MSH2
    Sebaceous adenoma reveals nuclear negativity for repair enzyme MSH2

It is mainly made up of completely differentiated sebocytes, with some basaloid epithelial cells.[1]

Diagnosis

Differential diagnosis

It may appear similar to sebaceous hyperplasia and sebaceoma.[1] It is not the same as adenoma sebaceum.[2]

See also

References

  1. 1 2 3 4 5 6 7 8 9 10 11 12 DE, Elder; D, Massi; RA, Scolyer; R, Willemze (2018). "3. Appendageal tumours: Sebaceous adenoma". WHO Classification of Skin Tumours. Vol. 11 (4th ed.). Lyon (France): World Health Organization. p. 213. ISBN 978-92-832-2440-2. Archived from the original on 2022-07-11. Retrieved 2022-08-09.
  2. ↑ Layton, Alison M.; Eadey, E. Anne; Zouboulis, Cristos C. (2016). "Part 8. 90. Acne". In Griffiths, Christopher E. M.; Barker, Jonathan; Bleiker, Tanya O; Chalmers, Robert; Creamer, Daniel (eds.). Rook's Textbook of Dermatology, 4 Volume Set. John Wiley & Sons. ISBN 978-1-118-44119-0. Archived from the original on 2022-08-11. Retrieved 2022-08-10.
External resources
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