Cortobenzolone

Cortobenzolone
Clinical data
Trade namesTuplix
Other namesBetamethasone salicylate; 9α-Fluoro-11β,16α,17α-trihydroxy-21-((2-hydroxybenzoyl)oxy)pregna-1,4-diene-3,20-dione
Drug classCorticosteroid; Glucocorticoid
Identifiers
IUPAC name
  • [2-[(8S,10S,11S,13S,14S,16R,17S)-9-Fluoro-11,16,17-trihydroxy-10,13-dimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2-hydroxybenzoate
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
FormulaC28H31FO8
Molar mass514.546 g·mol−1
3D model (JSmol)
SMILES
  • C[C@]12C[C@@H](C3([C@H]([C@@H]1C[C@H]([C@@]2(C(=O)COC(=O)C4=CC=CC=C4O)O)O)CCC5=CC(=O)C=C[C@@]53C)F)O
InChI
  • InChI=1S/C28H31FO8/c1-25-10-9-16(30)11-15(25)7-8-18-19-12-21(32)28(36,26(19,2)13-22(33)27(18,25)29)23(34)14-37-24(35)17-5-3-4-6-20(17)31/h3-6,9-11,18-19,21-22,31-33,36H,7-8,12-14H2,1-2H3/t18-,19-,21+,22-,25-,26-,27?,28-/m0/s1
  • Key:FVUHHROTFPGTFL-OHKAWVANSA-N

Cortobenzolone (brand name Tuplix), also known as betamethasone salicylate, is a synthetic glucocorticoid corticosteroid and corticosteroid ester which is marketed in Spain.[1][2][3]

References

  1. ↑ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 147–. ISBN 978-1-4757-2085-3.
  2. ↑ Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 119–. ISBN 978-3-88763-075-1.
  3. ↑ Negwer M, Scharnow HG (2001). Organic-chemical drugs and their synonyms: (an international survey). Wiley-VCH. p. 3523. ISBN 978-3-527-30247-5.


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