Quinestradol

Quinestradol
Clinical data
Trade namesColpovis, Colpovister, Pentovis
Other namesQuinestradiol; Quinestriol; Estriol 3-cyclopentyl ether; E3CPE
Routes of
administration		By mouth
Drug classEstrogen; Estrogen ether
ATC code
  • None
Identifiers
IUPAC name
  • (8R,9S,13S,14S,16R,17R)-3-cyclopentyloxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-16,17-diol
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.013.294
Edit this at Wikidata
Chemical and physical data
FormulaC23H32O3
Molar mass356.506 g·mol−1
3D model (JSmol)
SMILES
  • CC12CCC3C(C1CC(C2O)O)CCC4=C3C=CC(=C4)OC5CCCC5
InChI
  • InChI=1S/C23H32O3/c1-23-11-10-18-17-9-7-16(26-15-4-2-3-5-15)12-14(17)6-8-19(18)20(23)13-21(24)22(23)25/h7,9,12,15,18-22,24-25H,2-6,8,10-11,13H2,1H3/t18-,19-,20+,21-,22+,23+/m1/s1
  • Key:ODYKCPYPRCJXLY-PZORDLPLSA-N

Quinestradol (INN, BAN) (brand names Colpovis, Colpovister, Pentovis), also known as quinestradiol or quinestriol, as well as estriol 3-cyclopentyl ether (E3CPE), is a synthetic estrogen and estrogen ether which is no longer marketed.[1][2][3][4] It is the 3-cyclopentyl ether of estriol.[1] The medication has been studied in the treatment of stress incontinence in elderly women, with effectiveness observed.[3][4]

See also

References

  1. 1 2 Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 899–. ISBN 978-1-4757-2085-3.
  2. ↑ Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 905–. ISBN 978-3-88763-075-1.
  3. 1 2 Crosignani PG, Paoletti R, Sarrel PM, Wenger NK (6 December 2012). Women's Health in Menopause: Behaviour, Cancer, Cardiovascular Disease, Hormone Replacement Therapy. Springer Science & Business Media. pp. 245–. ISBN 978-94-011-1024-2.
  4. 1 2 Seifer DB (27 July 1999). Menopause: Endocrinology and Management. Springer Science & Business Media. pp. 161–. ISBN 978-1-59259-246-3.



This article is issued from Offline. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.