Sodium channel opener
A sodium channel opener is a type of drug which facilitates ion transmission through sodium channels.
Examples include toxins, such as aconitine, veratridine, batrachotoxin, robustoxin, palytoxin and ciguatoxins and insecticides (DDT and pyrethroids), which activate voltage-gated sodium channels (VGSCs), and solnatide (AP301), which activates the epithelial sodium channel (ENaC).[1]
See also
References
- ↑ Shabbir W, Tzotzos S, Bedak M, Aufy M, Willam A, Kraihammer M, Holzner A, Czikora I, Scherbaum-Hazemi P, Fischer H, Pietschmann H, Fischer B, Lucas R, Lemmens-Gruber R (2015). "Glycosylation-dependent activation of epithelial sodium channel by solnatide". Biochem. Pharmacol. 98 (4): 740–53. doi:10.1016/j.bcp.2015.08.003. PMID 26254591.
| Types |
| ||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Classes |
| ||||||||||||||||||||||||||||||||
This article is issued from Offline. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.