Hymecromone

Hymecromone (4-methylumbelliferone) is a drug used in bile therapy. It is used as choleretic and antispasmodic drugs and as a standard for the fluorometric determination of enzyme activity.[1]

Hymecromone
Clinical data
Other names4-Methylumbelliferone
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • 7-Hydroxy-4-methylchromen-2-one
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.001.806
Chemical and physical data
FormulaC10H8O3
Molar mass176.171 g·mol−1
3D model (JSmol)
  • CC1=CC(=O)OC2=C1C=CC(=C2)O
  • InChI=1S/C10H8O3/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5,11H,1H3 checkY
  • Key:HSHNITRMYYLLCV-UHFFFAOYSA-N checkY
  (verify)

Hymecromone is a crystalline solid with a melting point of 194–195 °C. It is soluble in methanol and glacial acetic acid.

See also

References
  1. Yang Y, Hamaguchi K (April 1980). "Hydrolysis of 4-methylumbelliferyl N-acetyl-chitotrioside catalyzed by hen and turkey lysozymes. pH dependence of the kinetics constants". Journal of Biochemistry. 87 (4): 1003–14. doi:10.1093/oxfordjournals.jbchem.a132833. PMID 7390976.


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