Actinomycin lactonase
The enzyme actinomycin lactonase (EC 3.1.1.39) catalyzes the reaction
- actinomycin + H2O actinomycinic monolactone
actinomycin lactonase | |||||||||
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Identifiers | |||||||||
EC no. | 3.1.1.39 | ||||||||
CAS no. | 37288-09-8 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is actinomycin lactonohydrolase.
References
- Hou CT, Perlman D (1970). "Microbial transformations of peptide antibiotics. V. Purification and properties of the actinomycin lactonase from Actinoplanes missouriensis". J. Biol. Chem. 245 (6): 1289–95. PMID 4191854.
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