Brunó Ferenc Straub

Brunó Ferenc Straub (5 January 1914 in Nagyvárad, Austria-Hungary (now Oradea, Romania) – 15 February 1996) was a biochemist. As a young scholar he was a research assistant of Albert Szent-Györgyi at the University of Szeged, and subsequently worked at the Molteno Institute, Cambridge, UK. He was the first to obtain actin in a relatively pure state.[1] He founded the Biological Research Centre in Szeged. He was the chairman of the Hungarian Presidential Council from 29 June 1988 to 23 October 1989. He proposed the theory of conformational selection in 1964,[2][3] the same year the Monod–Wyman–Changeux model was proposed.[4][5]

The native form of this personal name is Straub Brunó Ferenc. This article uses Western name order when mentioning individuals.
Brunó Ferenc Straub
6th Chairman of the Hungarian Presidential Council
In office
29 June 1988 – 23 October 1989
Preceded byKároly Németh
Succeeded byMátyás Szűrös
Personal details
Born(1914-01-05)5 January 1914
Nagyvárad, Austria-Hungary (now Oradea, Romania)
Died15 February 1996(1996-02-15) (aged 82)
NationalityHungarian
Political partyHungarian Socialist Workers Party
Spouse(s)Erzsébet Lichneckert (1940–1967)
Gertrud Szabolcsi (1972–1993)
Children2 daughters

References
  1. Straub BF (1942). Szent-Györgyi A (ed.). "Actin". Studies from the Institute of Medical Chemistry University Szeged. 1942. II: 3–15.
  2. Csermely, P.; Palotai, R.; Nussinov, T. (2010). "Induced fit, conformational selection and independent dynamic segments: an extended view of binding events". Trends Biochem. Sci. 35 (10): 539–546. doi:10.1016/j.tibs.2010.04.009. PMC 3018770.
  3. Orosz, F.; Vértessy, B. G. (2021). "What's in a name? From "fluctuation fit" to "conformational selection": rediscovery of a concept". Hist. Philos. Life Sci. 43: 88. doi:10.1007/s40656-021-00442-2. PMC 8270835.
  4. Changeux, J.-P. (1964). "Allosteric interactions interpreted in terms of quaternary structure". Brookhaven Symp. Biol. 17: 232–249. PMID 14246265.
  5. Monod, J; Wyman, J; Changeux, J.-P. (1965). "On the Nature of Allosteric Transitions — a Plausible Model". J. Mol. Biol. 12 (1): 88–118. doi:10.1016/S0022-2836(65)80285-6. PMID 14343300.
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