Ambuphylline

Ambuphylline
Names
	IUPAC name 1,3-dimethyl-7H-purine-2,6-dione : 2-amino-2-methylpropan-1-ol
	Other names Theophylline aminoisobutanol, bufylline
Identifiers
CAS Number	5634-34-4 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL2104089 ;
ChemSpider	20536 ;
ECHA InfoCard	100.024.616
KEGG	D02884 ;
PubChem CID	21850;
UNII	VOU5V0B772 ;
CompTox Dashboard (EPA)	DTXSID60204880 ;
	InChI InChI=1S/C7H8N4O2.C4H11NO/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13;1-4(2,5)3-6/h3H,1-2H3,(H,8,9);6H,3,5H2,1-2H3 Key: SEIRRUDMPNNSCY-UHFFFAOYSA-N ; InChI=1/C7H8N4O2.C4H11NO/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13;1-4(2,5)3-6/h3H,1-2H3,(H,8,9);6H,3,5H2,1-2H3 Key: SEIRRUDMPNNSCY-UHFFFAOYAX;
	SMILES O=C2N(c1nc[nH]c1C(=O)N2C)C.OCC(N)(C)C;
Properties
Chemical formula	C11H19N5O3
Molar mass	269.30 g/mol
Appearance	Crystalline, slightly yellowish white powder
Melting point	254 to 256 °C (489 to 493 °F; 527 to 529 K)
Solubility in water	Freely soluble.
Pharmacology
ATC code	R03DA10 (WHO)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Ambuphylline (or bufylline) is a combination of theophylline and aminoisobutanol used as a bronchodilator.[1] It also acts and may be used as a diuretic.[2]

References

Smith, J. R.; Jensen, J. (1946). "The effect of theophylline aminoisobutanol in the failing experimental heart". The Journal of Laboratory and Clinical Medicine. 31: 455–457. PMID 21022557.
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