Cirsilineol

Cirsilineol is a bioactive flavone isolated from Artemisia[1] and from Teucrium gnaphalodes.[2]

Cirsilineol
Names
IUPAC name
4′,5-Dihydroxy-3′,6,7-trimethoxyflavone
Systematic IUPAC name
5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-6,7-dimethoxy-4H-1-benzopyran-4-one
Other names
Eupatrin
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
UNII
  • InChI=1S/C18H16O7/c1-22-13-6-9(4-5-10(13)19)12-7-11(20)16-14(25-12)8-15(23-2)18(24-3)17(16)21/h4-8,19,21H,1-3H3
    Key: VKOSQMWSWLZQPA-UHFFFAOYSA-N
  • InChI=1S/C18H16O7/c1-22-13-6-9(4-5-10(13)19)12-7-11(20)16-14(25-12)8-15(23-2)18(24-3)17(16)21/h4-8,19,21H,1-3H3
    Key: VKOSQMWSWLZQPA-UHFFFAOYSA-N
  • COC1=C(C=CC(=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)OC)OC)O)O
Properties
C18H16O7
Molar mass 344.319 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References
  1. Sheng, X; Sun, Y; Yin, Y; Chen, T; Xu, Q (2008). "Cirsilineol inhibits proliferation of cancer cells by inducing apoptosis via mitochondrial pathway". The Journal of Pharmacy and Pharmacology. 60 (11): 1523–9. doi:10.1211/jpp/60.11.0014. PMID 18957174.
  2. Flavonoid Aglycones and Glycosides from Teucrium gnaphalodes. F. A. T. Barberán, M. I. Gil, F. Tomás, F. Ferreres and A. Arques, J. Nat. Prod., 1985, 48 (5), pages 859–860, doi:10.1021/np50041a040


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.