Digalactosyldiacylglycerol synthase

In enzymology, a digalactosyldiacylglycerol synthase (EC 2.4.1.241) is an enzyme that catalyzes the chemical reaction

UDP-galactose + 3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol UDP + 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn- glycerol
digalactosyldiacylglycerol synthase
Identifiers
EC no.2.4.1.241
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

Thus, the two substrates of this enzyme are UDP-galactose and 3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol, whereas its 3 products are UDP, [[3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn-]], and glycerol.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol 6-alpha-galactosyltransferase. Other names in common use include DGD1, DGD2, DGDG synthase (ambiguous), UDP-galactose-dependent DGDG synthase, UDP-galactose-dependent digalactosyldiacylglycerol synthase, and UDP-galactose:MGDG galactosyltransferase. This enzyme participates in glycerolipid metabolism.

References


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