Xylosyltransferase

References

  1. Götting, Christian; Kuhn, Joachim; Weilke, Christian; Brinkmann, Thomas; Kleesiek, Knut; Sollberg, Stephan; Huerkamp, Christina; Krieg, Thomas (June 1999). "Serum Xylosyltransferase: a New Biochemical Marker of the Sclerotic Process in Systemic Sclerosis". Journal of Investigative Dermatology. 112 (6): 919–924. doi:10.1046/j.1523-1747.1999.00590.x. ISSN 0022-202X.
  2. Poönighaus, Claudia; Ambrosius, Michael; Casanova, Javier Carrera; Prante, Christian; Kuhn, Joachim; Esko, Jeffrey D.; Kleesiek, Knut; Goötting, Christian (February 2007). "Human Xylosyltransferase II Is Involved in the Biosynthesis of the Uniform Tetrasaccharide Linkage Region in Chondroitin Sulfate and Heparan Sulfate Proteoglycans". Journal of Biological Chemistry. 282 (8): 5201–5206. doi:10.1074/jbc.m611665200. ISSN 0021-9258.

xylosyl transferase is the first enzyme involved in the biosynthesis of glycosaminoglycan chains, an important constituent of proteoglycans. There are two types of xylosyl transferases type I and type II.


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