Dysgammaglobulinemia

Dysgammaglobulinemia is a type of immune disorder characterized by a reduction in some types of gamma globulins, resulting in heightened susceptibility to some infectious diseases where primary immunity is antibody based.[1][2]

Dysgammaglobulinemia
SpecialtyHematology Edit this on Wikidata

It is distinguished from hypogammaglobulinemia, which is a reduction in all types of gamma globulins.[3]

Hyper IgM syndrome can be considered a form of dysgammaglobulinemia, because it results from a failure of transformation from IgM production to production of other antibodies, and so the condition can be interpreted as a reduction of the other types.

See also

References
  1. "Dysgammaglobulinemia" at Dorland's Medical Dictionary
  2. Dysgammaglobulinemia at eMedicine Dictionary
  3. "hypogammaglobulinemia" at Dorland's Medical Dictionary

Further reading
  • Raif S. Geha et al.: "Hyper Immunoglobulin M Immunodeficiency (Dysgammaglobulinemia)", Journal of Clinical Investigation, 1979 August; 64(2): 385–391, doi:10.1172/JCI109473. Accessed 2009-07-17.
  • Andre Cruchaud et al.: "The site of synthesis of the 19S T-globulins in dysgammaglobulinemia" (1962). Accessed 2009-07-17.


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