Eprazinone

Eprazinone (trade names Eftapan, Isilung, Mucitux) is a mucolytic and bronchospasm relieving drug.[1] It has been marketed in many European countries, but not in the US or United Kingdom.[2]

Eprazinone
Clinical data
Trade namesEftapan, Isilung, Mucitux
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • 3-[4-(2-ethoxy-2-phenyl-ethyl)piperazin-1-yl]-2-methyl-1-phenyl-propan-1-one
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
CompTox Dashboard (EPA)
ECHA InfoCard100.030.782
Chemical and physical data
FormulaC24H32N2O2
Molar mass380.532 g·mol−1
3D model (JSmol)
  • CCOC(CN1CCN(CC1)CC(C)C(=O)C2=CC=CC=C2)C3=CC=CC=C3
  • InChI=1S/C24H32N2O2/c1-3-28-23(21-10-6-4-7-11-21)19-26-16-14-25(15-17-26)18-20(2)24(27)22-12-8-5-9-13-22/h4-13,20,23H,3,14-19H2,1-2H3 ☒N
  • Key:BSHWLCACYCVCJE-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Indications

Indications include acute and chronic bronchitis, cough, rhinitis, and asthma.[2]

Side effects

Adverse effects include headache, somnolence, vertigo, heartburn, and nausea.[2]

References
  1. Spitzer W (June 1980). "[The efficacy of eprazinone dihydrochloride (Eftapan) in double-blind studies]". Fortschritte der Medizin. 98 (22): (871-4). PMID 6997154.
  2. Schlesser JL (1991). Drugs Available Abroad, 1st Edition. Derwent Publications Ltd. p. 76. ISBN 0-8103-7177-4.
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