Haplogroup C-M130

Haplogroup C is a major Y-chromosome haplogroup, defined by UEPs M130/RPS4Y711, P184, P255, and P260, which are all SNP mutations. It is one of two primary branches of Haplogroup CF alongside Haplogroup F. Haplogroup C is found in ancient populations on every continent except Africa and is the predominant Y-DNA haplogroup among males belonging to many peoples indigenous to East Asia, Central Asia, Siberia, North America and Australia as well as a some populations in Europe, the Levant, and later Japan.[1] The haplogroup is also found with moderate to low frequency among many present-day populations of Southeast Asia, South Asia, and Southwest Asia.

This article is about the human Y-DNA haplogroup. For the human mtDNA haplogroup, see Haplogroup C (mtDNA).
Haplogroup C
Possible time of origin53,000 years BP
Possible place of originSouthwest Asia, via out-of-Africa migrations[1][2]
AncestorCF
DescendantsC1 F3393/Z1426 (previously CxC3)
C2 (previously C3*) M217[3]
Defining mutationsM130/RPS4Y711, P184, P255, P260

In addition to the basal paragroup C*, this haplogroup now has two major branches: C1 (F3393/Z1426; previously CxC3, i.e. old C1, old C2, old C4, old C5 and old C6) and C2 (M217; the former C3).

Origins

Haplogroup C-M130 likely originates from an exodus of modern humans out of Africa, which spread east from Southwest Asia and gradually colonized South Asia, East Asia and Oceania. Research is divided as to how this migration took place; most studies support a Northern Route through Siberia while others support a Southern Route hypothesis, in which the carriers of haplogroup C migrated along the coasts of India and Southeast Asia to get to China.[2]

Haplogroup C-M130 seems to have come into existence shortly after SNP mutation M168 occurred for the first time, bringing the modern Haplogroup CT into existence, from which Haplogroup CF, and in turn Haplogroup C, derived. This was probably at least 60,000 years ago.

Haplogroup C-M130 attains its highest frequencies among the indigenous populations of Kazakhstan, Mongolia, the Russian Far East, Polynesia, certain groups of Australia, and at moderate frequency in Korea and Manchu people. It is therefore hypothesized that Haplogroup C-M130 either originated or underwent its longest period of evolution in the greater Central Asian region or in Southeast Asian regions. Its expansion in East Asia is suggested to have started approximately 40,000 years ago.[2]

Males carrying C-M130 are believed to have migrated to the Americas some 6,000-8,000 years ago, and was carried by Na-Dené-speaking peoples into the northwest Pacific coast of North America.

Asia is also the area in which Haplogroup D-M174 is concentrated. However, D-M174 is more closely related to haplogroup E than to C-M130 and the geographical distributions of Haplogroups C-M130 and D-M174 are entirely and utterly different, with various subtypes of Haplogroup C-M130 being found at high frequency amongst modern Kazakhs and Mongolians as well as in some Indigenous peoples of the Americas, Manchurians. It is also found at a medium frequency in Koreans, indigenous inhabitants of the Russian Far East, certain Aboriginal Australians groups and at moderate frequencies elsewhere throughout Asia and Oceania. Carriers of Haplogroup C among the later Jōmon people of Japan and certain Paleolithic and Neolithic Europeans carried C1a, C1b, and C1a2. Whereas Haplogroup D is found at high frequencies only amongst Tibetans, Japanese peoples, and Andaman Islanders, and has been found neither in India nor among the aboriginal inhabitants of the Americas or Oceania.[1]

According to Sakitani et al., haplogroup C-M130 originated in Central Asia and spread from there into other parts of Eurasia and into parts of Australia. It is suggested that C-M130 was found in Eastern Eurasian hunter gatherers as well as in ancient samples of East and Southeast Asia and Europe.[1]

Structure

C* (M130/Page51/RPS4Y711, M216)

  • C1 (F3393)
    • C1a (CTS11043)
      • C1a1 (M8)
        • C1a1a (P121)
          • C1a1a1 (CTS9336)
            • C1a1a1a (CTS6678) Japan, South Korea (Seoul)
            • C1a1a1b (Z1356) Japan
          • C1a1a2 (Z45460) China (Liaoning)
      • C1a2 (previously C6) - (V20)
        • C1a2a (V182)
          • C1a2a1 (V222)
          • C1a2a2 (Z29329)
        • C1a2b (Z38888) Ukraine
    • C1b (F1370)
      • C1b1 (K281)
        • C1b1a (B66/Z16458)
          • C1b1a1 (previously C5) - (M356)
          • C1b1a2 (B65)
      • C1b2 (B477/Z31885)
        • C1b2a (previously C2) - (M38)
          • C1b2a1 (M208)
            • C1b2a1a (P33)
            • C1b2a1b (P54)
        • C1b2b (previously C4) - (M347)
          • C1b2b1 (M210)
  • C2 (previously C3) - (M217)
    • C2a (M93)
    • C2b (L1373/F1396)
      • C2b1
        • C2b1a
          • C2b1a1
            • C2b1a1a (P39)
          • C2b1a2 (previously C3c) - (M48)
    • C2c (C-F1067)
      • C2c1 (F2613/Z1338)
        • C2c1a (Z1300)
          • C2c1a1
            • C2c1a1a
              • C2c1a1a1 (M407)
  • Other, untaxonomised subclades:
    • C-P343: outside C1a1 (M8), C1b2a (M38), C1b1a1 (previously C5; M356), C1b2b (previously C4; M347), and C2 (ex-C3; M217), but its relation to other branches is not yet tested.[4]
    • C-P55: outside C1b2a (M38), but its relation to other branches has not yet been verified, and;[5]

(The above phylogenetic structure of haplogroup C-M130 subclades is based on the ISOGG 2015 tree, YCC 2008 tree and subsequent published research.[6][7])

Distribution
Projected spatial frequency distribution for haplogroup C in East Asia.[8]

The distribution of Haplogroup C-M130 is generally limited to populations of Siberia, parts of East Asia, Oceania, and the Americas. Due to the tremendous age of Haplogroup C, numerous secondary mutations have had time to accumulate, and many regionally important subbranches of Haplogroup C-M130 have been identified.

Up to 46% of Aboriginal Australian males carried either basal C* (C-M130*), C1b2b* (C-M347*) or C1b2b1 (C-M210), before contact with and significant immigration by Europeans, according to a 2015 study by Nagle et al.[9] That is, 20.0% of the Y-chromosomes of 657 modern individuals, before 56% of those samples were excluded as "non-indigenous". C-M130* was apparently carried by up to 2.7% of Aboriginal males before colonisation; 43% carried C-M347, which has not been found outside Australia. The other haplogroups of Aboriginal Australians is similar to Papuans and other Negritos (Haplogroup S-M230 and M-P256).[9][10]

Low levels of C-M130* are carried by males:

Basal C1a* (CTS11043) was found in an Upper Paleolithic Europeans (Aurignacians), GoyetQ116-1 and Pestera Muerii2.[12]

C1b was identified in prehistoric remains, dating from 34,000 years BP, found in Russia and known as "Kostenki 14".[13]

Haplogroup C2 (M217) – the most numerous and widely dispersed C lineage – was once believed to have originated in Central Asia, spread from there into Northern Asia and the Americas while other theory it originated from East Asia.[6] C-M217 stretches longitudinally from Central Europe and Turkey, to the Wayuu people of Colombia and Venezuela, and latitudinally from the Athabaskan peoples of Alaska to Vietnam to the Malay Archipelago. Found at low concentrations in Eastern Europe, where it may be a legacy of the invasions/migrations of the Huns, Turks and/or Mongols during the Middle Ages. Found at especially high frequencies in Buryats, Daurs, Hazaras, Itelmens, Kalmyks, Koryaks, Manchus, Mongolians, Oroqens, and Sibes, with a moderate distribution among other Tungusic peoples, Koreans, Ainus, Nivkhs, Altaians, Tuvinians, Uzbeks, Han Chinese, Tujia, Hani, and Hui.[14][15][16][17][18][19][20] The highest frequencies of Haplogroup C-M217 are found among the populations of Mongolia and Far East Russia, where it is the modal haplogroup. Haplogroup C-M217 is the only variety of Haplogroup C-M130 to be found among Native Americans, among whom it reaches its highest frequency in Na-Dené populations.

Other subclades are specific to certain populations, within a restricted geographical range; even where these other branches are found, they tend to appear as a very low-frequency, minor component of the palette of Y-chromosome diversity within those territories:

  • C-M8 (C1a1), is now found regularly only with low frequency (approximately 5%; range 3.3% — 10% of all samples) in Japan. It also has been found in an academic study in one individual on Jeju Island and in commercial testing in one individual who has reported an origin in Liaoning province of China and one individual who has reported an origin in Seoul. The ancient Jōmon people had a frequency of about 30% of C1a1.
  • C-V20 (C1a2; previously C6) is found at low frequencies amongst Europeans.[21] The 7,000-year-old remains of a hunter-gatherer from La Braña (modern Asturias, Spain) carried it,[22] and C1a2 was also present in Hungary at around the same time.[6][23] In 2016, a 35,000-year-old remains of a hunter gatherer from the Goyet Caves (Namur, Belgium) and a 30,000-year-old remains of a hunter gatherer from Dolni Vestonice (Vestonice16, Moravia, Czech Republic) were found with this haplogroup.[24]
  • C-B66/Z16458 (C1b1a) is found at low frequencies in South Asia, Central Asia, and Southwest Asia.[17][25][26][27][28][29]
  • C-M356 (C1b1a1; previously C5) has been detected with low frequency in samples from India, Nepal,[25][26] Pakistan, Afghanistan, Arabia,[27][28] and northern China.[2][6]
  • C-M38 (C1b2a; previously C2), among some local populations within Indonesia, Melanesia (especially New Guinea), Micronesia, and some islands of Polynesia, C-M38 has become the modal haplogroup, probably due to severe founder effects and genetic drift.[6]
  • C-P33 (C1b2a1a): found at high frequencies among Polynesian males.[15][30]
  • C-P55 (C1b3) is found at low frequency in the New Guinea Highlands.[5]
  • C-M93 (C2a) is found sporadically in Japanese people.[17][31]
  • C-L1373/F1396 (C2b) has been identified in Central Asia.
  • C-P39 (C2b1a1a) is found among several indigenous peoples of North America, including some Na-Dené-, Algonquian- and Siouan-speaking populations.[6][32]
  • C-M48 (C2b1b; previously C3c) is found at high frequencies in northern Tungusic peoples, Kazakhs, Oirats, Kalmyks, Mongolians, Yukaghirs, Nivkhs, Koryaks, Itelmens, and Udegeys, with a moderate distribution among southern Tungusic peoples, Buryats, Tuvinians, Yakuts, Chukchi, Kyrgyz, Uyghurs, Uzbeks, Karakalpaks, and Tajiks.[18][33][34]
  • C-P53.1 (C2c) is borne by about 10% of Xinjiang Sibe males, with low frequency in Mongolia and among Evenks, Ningxia Hui, Xizang Tibetan, Xinjiang Uyghur, and Gansu Han.[2]
  • C-F2613/Z1338 (C2e): both Central Asia and East Asia.[6]
  • C-M407 (C2e1a1a) has been found with high frequency among Barghuts, Buryats, Soyots, and Khamnigans, moderate frequency among other Mongols and Kalmyks, and low frequency in Armenian, Bai, Cambodian, Evenk,[35] Han Chinese, Japanese, Kazakh, Korean, Manchu, Teleut,[35] Tujia, Tuvinian,[35] Uyghur, and Yakut populations.[2][17]
  • C-P343 occurs at a high frequency among males from Lembata (17.4% of 92 samples), with lower frequencies in Flores, Pantar, and Timor.[4] P343 is outside C1a1 (M8), C1b2a (M38), C2 (ex-C3; M217), C1b2b (previously C4; M347), or C1b1a1 (previously C5; M356), but its relation to other branches is not yet tested.[4]
  • Unspecified instances of C-M130, which possibly may belong to one of the above subclades, include:
    • Kayser et al. (2006) found C-M130(xM38, 390.1del, M217) in 10.3% (4/39) of a sample of ethnic minority groups from the Philippines, 10.0% (6/60) of a sample from Arnhem Land, 6.5% (2/31) of a sample from Nusa Tenggara, 5.3% (3/57) of a sample from Sumatra, 3.0% (1/33) of a sample from the Papua New Guinea coast, 2.9% (1/34) of a sample from the Moluccas, 1.9% (1/53) of a sample from Java, and 0.9% (1/107) of a sample from Fiji.[36]
    • C-RPS4Y (now C-RPS4Y711) (xM38) Y-DNA is quite common among populations of the Indonesian province of East Nusa Tenggara and independent East Timor: 13/31 = 41.9% Lembata, 16/71 = 22.5% Flores, 5/43 = 11.6% Solor, 10/96 = 10.4% Adonara, 3/39 = 7.7% East Timor, 1/26 = 3.8% Alor, 1/38 = 2.6% Pantar. All C-RPS4Y(xM38) individuals except the singleton from Alor were described as Austronesian speakers.[37]
    • C-RPS4Y (now C-RPS4Y711) (xM38, M217) Y-DNA occurs, according to a study published in 2010, at rather high frequencies in most populations of central Indonesia (115/394 = 29.2% Flores, 21/92 = 22.8% Lembata, 19/86 = 22.1% Borneo, 6/54 = 11.1% Mandar, 1/9 = 11.1% Timor, but only 1/350 = 0.3% Sumba). C-RPS4Y(xM38, M217) Y-DNA generally becomes rare toward the west (2/61 = 3.3% Java, 1/32 = 3.1% Malaysia, 9/641 = 1.4% Balinese, 0/38 Batak Toba, 0/60 Nias, but 10/74 = 13.5% Mentawai) and toward the east (1/28 = 3.6% Alor, 0/30 Moluccas, 1/15 = 6.7% PNG Coast, 0/33 PNG Highland, 0/10 Nasioi, 0/44 Maewo (Vanuatu), 1/16 = 6.3% Micronesia, 0/64 Polynesia).[38]
    • C-RPS4Y711(xM8, M217) Y-DNA has been found in 17% (6/35) of a sample of Yao from Bama, Guangxi in south-central China, 4/35 = 11% of a sample of Hui and 2/70 = 3% of a pair of samples of Uyghur from northwestern China, and 3/45 = 7% of a sample of Hezhe and 1/26 = 4% of a sample of Ewenki from northeastern China.[14]
    • C-RPS4Y711(xM8, M38, M217) has been found in 48.5% (16/33) of a sample of indigenous Australians, 20% (12/60) of a sample of Yao, 6.1% (3/49) of a sample of Tujia, 5.9% (1/17) of a sample of Micronesians, 5.5% (3/55) of a sample of eastern Indonesians, 4.0% (1/25) of a sample of western Indonesians, 3.3% (3/91) of a sample of Sri Lankans, 3.1% (1/32) of a sample of Malays, 2.5% (10/405) of a sample of Indians, 2.2% (1/46) of a sample of Papua New Guineans, 1.7% (1/58) of a sample of Miao, and 1.5% (1/67) of a sample of Uyghurs.[15]
    • Zhong et al. (2010) have found C-M130(xM8, M38, M217, M347, M356, P55) Y-DNA in 9.09% (1/11) of a sample of Mulao from Guangxi, 8.20% (5/61) of a sample of Hui from Ningxia, 7.96% (9/113) of a sample of Yao from Guangxi, 7.69% (2/26) of a sample of Tujia from Hubei, 6.90% (2/29) of a sample of Shui from Guizhou, 3.28% (2/61) of a sample of Xibe from Xinjiang, 1.45% (1/69) of a sample of Zhuang from Guangxi, 0.92% (1/109) of a sample of Buyi from Guizhou, 0.87% (2/231) of a sample of Han from Guizhou, and 0.74% (1/136) of a sample of Han from Yunnan.[2] A majority of these individuals share an identical 8-loci Y-STR haplotype: DYS19=15, DYS389I=12, DYS389b=16, DYS388=13, DYS390=21, DYS391=10, DYS392=11, DYS393=12.[2]
    • Di Cristofaro et al. (2013) have found C-M130(xC2-PK2/M386, C1b1a1-M356) in 1.9% (1/53) of a sample of Pashtun from Kunduz, Afghanistan and in 1.4% (1/69) of a sample of Hazara from Bamiyan, Afghanistan.[39]
    • Wang et al. (2014) have found C-M130(xM105, M38, M217, M347, M356) in 5.6% (1/18) of a sample of Horpa Qiang from Danba County of Sichuan, China and in 2.2% (1/46) of a sample of Khams Tibetans from Xinlong County of Sichuan, China.[40] The Y-STR haplotypes of these two individuals match the modal C* haplotype from the study by Zhong et al. (2010) at every comparable locus.[40]
    • "C-M216", an SNP that is now regarded as synonymous with C-M130 – (xM8, M38, M217, M210, M356) have been found in 3.9% (3/77) of a sample of the general population of Kathmandu, Nepal.[25] Other examples of C-M216 have been reported among Mongol and Turkic peoples, including the: Jalairs, Kazakhs, Merkits, Jochids and Uzbeks;

Phylogenetics

Phylogenetic history
Main article: Conversion table for Y chromosome haplogroups

Prior to 2002, there were in academic literature at least seven naming systems for the Y-Chromosome Phylogenetic tree. This led to considerable confusion. In 2002, the major research groups came together and formed the Y-Chromosome Consortium (YCC). They published a joint paper that created a single new tree that all agreed to use. The table below brings together all of these works at the point of the landmark 2002 YCC Tree. This allows a researcher reviewing older published literature to quickly move between nomenclatures.

YCC 2002/2008 (Shorthand) (α) (β) (γ) (δ) (ε) (ζ) (η) YCC 2002 (Longhand) YCC 2005 (Longhand) YCC 2008 (Longhand) YCC 2010r (Longhand) ISOGG 2006 ISOGG 2007 ISOGG 2008 ISOGG 2009 ISOGG 2010 ISOGG 2011 ISOGG 2012
C-M21610V1F16Eu6H1CC*CCCCCCCCCC
C-M810V1F19Eu6H1CC1C1C1C1C1C1C1C1C1C1C1
C-M3810V1F16Eu6H1CC2*C2C2C2C2C2C2C2C2C2C2
C-P3310V1F18Eu6H1CC2aC2aC2a1C2a1C2aC2aC2a1C2a1C2a1removedremoved
C-P4410V1F17Eu6H1CC3*C3C3C3C3C3C3C3C3C3C3
C-M9310V1F17Eu6H1CC3aC3aC3aC3aC3aC3aC3aC3aC3aC3aC3a1
C-M20810V1F17Eu6H1CC3bC2bC2aC2aC2bC2bC2aC2aC2aC2aC2a
C-M21036V1F17Eu6H1CC3cC2cC4aC4aC4bC4bC4aC4aC4aC4aC4a

Research publications

The following research teams per their publications were represented in the creation of the YCC Tree.

Notable members

One particular haplotype within Haplogroup C-M217 has received a great deal of attention for the possibility that it may represent direct patrilineal descent from Genghis Khan.

A research paper published in 2017 - "Genetic trail for the early migrations of Aisin Gioro, the imperial house of the Qing dynasty"[41] confirmed that the Aisin Gioro clan belongs to haplogroup C3b1a3a2-F8951, a brother branch of C3*-Star Cluster (currently named as C3b1a3a1-F3796, once linked to Genghis Khan).

See also

Genetics

Y-DNA C Subclades

Y-DNA backbone tree

References
  1. 崎谷満『DNA・考古・言語の学際研究が示す新・日本列島史』（勉誠出版　2009年）(in Japanese)
  2. Zhong H, Shi H, Qi XB, et al. (July 2010). "Global distribution of Y-chromosome haplogroup C-M130 reveals the prehistoric migration routes of African exodus and early settlement in East Asia". J. Hum. Genet. 55 (7): 428–35. doi:10.1038/jhg.2010.40. PMID 20448651. "At present, most of the archaeological and genetic evidence supports that the earliest African exodus went out of Africa via the Red Sea and then rapidly migrated to mainland Southeast Asia through the Indian coastline, and eventually reached Oceania.36, 37, 38, 39 Recent Y-chromosome and mitochondrial DNA analysis in Australia and New Guinea has shown that Hg C is likely one of the earliest Out-of-Africa founder types,12 which was also proposed in another study,6 and that mitochondrial DNA lineages consisting of the founder types (M and N) are dated to approximately 50–70 KYA.12" ... "We propose that Hg C was derived from the African exodus and gradually colonized South Asia, Southeast Asia, Oceania and East Asia by a single Paleolithic migration from Africa to Asia and Oceania, which occurred more than 40 KYA."
  3. "ISOGG 2018 Y-DNA Haplogroup C".
  4. Tumonggor, Meryanne K; Karafet, Tatiana M; Downey, Sean; et al. (2014). "Isolation, contact and social behavior shaped genetic diversity in West Timor". Journal of Human Genetics. 59 (9): 1–10. doi:10.1038/jhg.2014.62. PMC 4521296. PMID 25078354.
  5. Scheinfeldt, L.; Friedlaender, F; Friedlaender, J; Latham, K; Koki, G; Karafet, T; Hammer, M; Lorenz, J (2006). "Unexpected NRY Chromosome Variation in Northern Island Melanesia". Molecular Biology and Evolution. 23 (8): 1628–41. doi:10.1093/molbev/msl028. PMID 16754639.
  6. ISOGG, 2015 "Y-DNA Haplogroup C and its Subclades – 2015" (15 September 2015).
  7. Karafet TM, Mendez FL, Meilerman MB, Underhill PA, Zegura SL, Hammer MF (2008). "New binary polymorphisms reshape and increase resolution of the human Y chromosomal haplogroup tree". Genome Research. 18 (5): 830–8. doi:10.1101/gr.7172008. PMC 2336805. PMID 18385274.
  8. Wang, CC; Li, H (2013). "Inferring human history in East Asia from Y chromosomes". Investig Genet. 4 (1): 11. doi:10.1186/2041-2223-4-11. PMC 3687582. PMID 23731529.
  9. Nagle, N.; et al. (2015). "Antiquity and diversity of aboriginal Australian Y-chromosomes". American Journal of Physical Anthropology. 159 (3): 367–81. doi:10.1002/ajpa.22886. PMID 26515539. S2CID 2225529.
  10. Hudjashov G, Kivisild T, Underhill PA, et al. (May 2007). "Revealing the prehistoric settlement of Australia by Y chromosome and mtDNA analysis". Proc. Natl. Acad. Sci. U.S.A. 104 (21): 8726–30. Bibcode:2007PNAS..104.8726H. doi:10.1073/pnas.0702928104. PMC 1885570. PMID 17496137.
  11. Cognoms Catalans, n.d., Resultat (15 September 2015). (The Cognoms Catalans project, which researches "genetic surnames" in Catalonia, Valencia and the Balearic Islands, is based at Universitat Pompeu Fabra, Barcelona.)
  12. Fu, Q.; Posth, C.; Hajdinjak, M.; Petr, M.; Mallick, S.; Fernandes, D.; Furtwängler, A.; Haak, W.; Meyer, M.; Mittnik, A.; Nickel, B.; Peltzer, A.; Rohland, N.; Slon, V.; Talamo, S.; Lazaridis, I.; Lipson, M.; Mathieson, I.; Schiffels, S.; Skoglund, P.; Derevianko, A. P.; Drozdov, N.; Slavinsky, V.; Tsybankov, A.; Cremonesi, R. G.; Mallegni, F.; Gély, B.; Vacca, E.; González Morales, M. R.; et al. (2016). "The genetic history of Ice Age Europe". Nature. 534 (7606): 200–205. Bibcode:2016Natur.534..200F. doi:10.1038/nature17993. PMC 4943878. PMID 27135931.
  13. Seguin-Orlando, A.; et al. (2014). "Genomic structure in Europeans dating back at least 36,200 years" (PDF). Science. 346 (6213): 1113–1118. Bibcode:2014Sci...346.1113S. doi:10.1126/science.aaa0114. PMID 25378462. S2CID 206632421. Archived from the original (PDF) on 2016-08-29.
  14. Xue Y, Zerjal T, Bao W, et al. (April 2006). "Male demography in East Asia: a north-south contrast in human population expansion times". Genetics. 172 (4): 2431–9. doi:10.1534/genetics.105.054270. PMC 1456369. PMID 16489223.
  15. Hammer MF, Karafet TM, Park H, et al. (2006). "Dual origins of the Japanese: common ground for hunter-gatherer and farmer Y chromosomes". J. Hum. Genet. 51 (1): 47–58. doi:10.1007/s10038-005-0322-0. PMID 16328082.
  16. Tajima, Atsushi; Hayami, Masanori; Tokunaga, Katsushi; Juji, T; Matsuo, M; Marzuki, S; Omoto, K; Horai, S (2004). "Genetic origins of the Ainu inferred from combined DNA analyses of maternal and paternal lineages". Journal of Human Genetics. 49 (4): 187–193. doi:10.1007/s10038-004-0131-x. PMID 14997363.
  17. Sengupta S, Zhivotovsky LA, King R, et al. (February 2006). "Polarity and temporality of high-resolution y-chromosome distributions in India identify both indigenous and exogenous expansions and reveal minor genetic influence of Central Asian pastoralists". Am. J. Hum. Genet. 78 (2): 202–21. doi:10.1086/499411. PMC 1380230. PMID 16400607.
  18. Lell JT, Sukernik RI, Starikovskaya YB, et al. (January 2002). "The dual origin and Siberian affinities of Native American Y chromosomes". Am. J. Hum. Genet. 70 (1): 192–206. doi:10.1086/338457. PMC 384887. PMID 11731934.
  19. Wells RS, Yuldasheva N, Ruzibakiev R, et al. (August 2001). "The Eurasian heartland: A continental perspective on Y-chromosome diversity". Proc. Natl. Acad. Sci. U.S.A. 98 (18): 10244–9. Bibcode:2001PNAS...9810244W. doi:10.1073/pnas.171305098. PMC 56946. PMID 11526236.
  20. Nasidze I, Quinque D, Dupanloup I, Cordaux R, Kokshunova L, Stoneking M (December 2005). "Genetic evidence for the Mongolian ancestry of Kalmyks". Am. J. Phys. Anthropol. 128 (4): 846–54. doi:10.1002/ajpa.20159. PMID 16028228. S2CID 27115596.
  21. Scozzari R, Massaia A, D'Atanasio E, Myres NM, Perego UA, et al. (2012). "Molecular Dissection of the Basal Clades in the Human Y Chromosome Phylogenetic Tree". PLOS ONE. 7 (11): e49170. Bibcode:2012PLoSO...749170S. doi:10.1371/journal.pone.0049170. PMC 3492319. PMID 23145109.
  22. "Dienekes' Anthropology Blog: Brown-skinned, blue-eyed, Y-haplogroup C-bearing European hunter-gatherer from Spain (Olalde et al. 2014)". 2014-01-26.
  23. http://biorxiv.org/content/biorxiv/early/2015/02/10/013433.full.pdf
  24. Fu, Qiaomei; et al. (2016). "The genetic history of Ice Age Europe". Nature. 534 (7606): 200–5. Bibcode:2016Natur.534..200F. doi:10.1038/nature17993. PMC 4943878. PMID 27135931.
  25. Gayden, Tenzin; Cadenas, Alicia M.; Regueiro, Maria; Singh, NB; Zhivotovsky, LA; Underhill, PA; Cavalli-Sforza, LL; Herrera, RJ (2007). "The Himalayas as a Directional Barrier to Gene Flow". American Journal of Human Genetics. 80 (5): 884–894. doi:10.1086/516757. PMC 1852741. PMID 17436243.
  26. Fornarino, Simona; Pala, Maria; Battaglia, Vincenza; et al. (2009). "Mitochondrial and Y-chromosome diversity of the Tharus (Nepal): a reservoir of genetic variation". BMC Evolutionary Biology. 9: 154. doi:10.1186/1471-2148-9-154. PMC 2720951. PMID 19573232.
  27. Cadenas, Alicia M; Zhivotovsky, Lev A; Cavalli-Sforza, Luca L; Underhill, PA; Herrera, RJ (2008). "Y-chromosome diversity characterizes the Gulf of Oman". European Journal of Human Genetics. 16 (3): 374–386. doi:10.1038/sj.ejhg.5201934. PMID 17928816.
  28. Abu-Amero, Khaled K; Hellani, Ali; González, Ana M; Larruga, Jose M; Cabrera, Vicente M; Underhill, Peter A (2009). "Saudi Arabian Y-Chromosome diversity and its relationship with nearby regions". BMC Genetics. 10: 59. doi:10.1186/1471-2156-10-59. PMC 2759955. PMID 19772609.
  29. Karafet, T. M.; Mendez, F. L.; Meilerman, M. B.; Underhill, P. A.; Zegura, S. L.; Hammer, M. F. (2008). "New binary polymorphisms reshape and increase resolution of the human Y chromosomal haplogroup tree". Genome Research. 18 (5): 830–8. doi:10.1101/gr.7172008. PMC 2336805. PMID 18385274.
  30. Cox MP, Redd AJ, Karafet TM, et al. (October 2007). "A Polynesian motif on the Y chromosome: population structure in remote Oceania". Hum. Biol. 79 (5): 525–35. doi:10.1353/hub.2008.0004. hdl:1808/13585. PMID 18478968. S2CID 4834817.
  31. Underhill PA, Shen P, Lin AA, et al. (November 2000). "Y chromosome sequence variation and the history of human populations". Nat. Genet. 26 (3): 358–61. doi:10.1038/81685. PMID 11062480. S2CID 12893406.
  32. Zegura SL, Karafet TM, Zhivotovsky LA, Hammer MF (January 2004). "High-resolution SNPs and microsatellite haplotypes point to a single, recent entry of Native American Y chromosomes into the Americas". Mol. Biol. Evol. 21 (1): 164–75. doi:10.1093/molbev/msh009. PMID 14595095.
  33. Pakendorf B, Novgorodov IN, Osakovskij VL, Danilova AP, Protod'jakonov AP, Stoneking M (October 2006). "Investigating the effects of prehistoric migrations in Siberia: genetic variation and the origins of Yakuts". Hum. Genet. 120 (3): 334–53. doi:10.1007/s00439-006-0213-2. PMID 16845541. S2CID 31651899.
  34. Khar'kov VN, Stepanov VA, Medvedev OF, et al. (2008). "[The origin of Yakuts: analysis of Y-chromosome haplotypes]". Mol. Biol. (Mosk.) (in Russian). 42 (2): 226–37. PMID 18610830.
  35. Boris Malyarchuk, Miroslava Derenko, Galina Denisova, et al., "Phylogeography of the Y-chromosome haplogroup C in northern Eurasia." Annals of Human Genetics (2010) 74,539–546. doi: 10.1111/j.1469-1809.2010.00601.x.
  36. Manfred Kayser, Silke Brauer, Richard Cordaux, et al. (2006), "Melanesian and Asian Origins of Polynesians: mtDNA and Y Chromosome Gradients Across the Pacific." Mol. Biol. Evol. 23(11):2234–2244. doi:10.1093/molbev/msl093
  37. Mona, Stefano; Grunz, Katharina E.; Brauer, Silke; et al. (2009). "Genetic Admixture History of Eastern Indonesia as Revealed by Y-Chromosome and Mitochondrial DNA Analysis". Mol. Biol. Evol. 26 (8): 1865–1877. doi:10.1093/molbev/msp097. PMID 19414523.
  38. Karafet Tatiana M.; Hallmark Brian; Cox Murray P.; et al. (2010). "Major East–West Division Underlies Y Chromosome Stratification across Indonesia". Mol. Biol. Evol. 27 (8): 1833–1844. doi:10.1093/molbev/msq063. PMID 20207712. S2CID 4819475.
  39. J D Cristofaro et al., 2013, "Afghan Hindu Kush: Where Eurasian Sub-Continent Gene Flows Converge", http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0076748
  40. Wang C-C, Wang L-X, Shrestha R, Zhang M, Huang X-Y, et al. (2014), "Genetic Structure of Qiangic Populations Residing in the Western Sichuan Corridor." PLoS ONE 9(8): e103772. doi:10.1371/journal.pone.0103772
  41. Wei, Lan-Hai; Yan, Shi; Yu, Ge; Huang, Yun-Zhi; Yao, Da-Li; Li, Shi-Lin; Jin, Li; Li, Hui (2017). "Genetic trail for the early migrations of Aisin Gioro, the imperial house of the Qing dynasty". J Hum Genet. 62 (Mar 62(3)): 407–411. doi:10.1038/jhg.2016.142. PMID 27853133. S2CID 7685248.

Sources for conversion tables
Wikimedia Commons has media related to Haplogroup C of Y-DNA.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.