Haplogroup CF

Haplogroup CF
Haplogroup CF
Possible time of origin	75,000-70,000 BP
Possible place of origin	Possibly Africa[1]
Ancestor	CT
Descendants	C, F
Defining mutations	P143

Haplogroup CF, also known as CF-P143 and CT(xDE), is a human Y-chromosome DNA haplogroup. This paternal lineage is defined by the SNP P143. The clade's existence and distribution are inferred from the fact that haplogroups descended from CF include most human male lineages in Eurasia, Oceania and The Americas.

CF is an immediate descendant of the Haplogroup CT (CT-M168), and is the sibling of Haplogroup DE (DE-YAP). It is the immediate ancestor of both Haplogroup C and Haplogroup F.[2]

There are, as yet, no confirmed cases of living individuals or human remains belonging to the basal, undivergent haplogroup CF*. In the year 2017, C-M217 (C2) & C-M130 were reported among males belonging to the Shan peoples, who are concentrated in central-east Burma (as well as neighboring parts of China, Laos and Thailand).[3] However, the researchers concerned (Brunelli et al.) did not rule out all other subclades of CF, such as haplogroup F, in these particular cases. (In haplogroup F2 has previously been identified in the same geographical region.[4])

Distribution

Migration of Haplogroup C.
The geographical development and distribution of Haplogroup F.

References

Haber, Marc; Jones, Abigail L; Connell, Bruce A; Arciero, Elena; Yang, Huanming; Thomas, Mark G; Xue, Yali; Tyler-Smith, Chris (2019). "A Rare Deep-Rooting D0 African Y-Chromosomal Haplogroup and Its Implications for the Expansion of Modern Humans Out of Africa". Genetics. 212 (4): 1421–1428. doi:10.1534/genetics.119.302368. PMC 6707464. PMID 31196864.
Underhill PA, Kivisild T (2007). "Use of Y chromosome and mitochondrial DNA population structure in tracing human migrations". Annu. Rev. Genet. 41: 539–64. doi:10.1146/annurev.genet.41.110306.130407. PMID 18076332.
Brunelli, Andrea (July 24, 2017). "Y chromosomal evidence on the origin of northern Thai people". PLOS ONE. 12 (7): e0181935. Bibcode:2017PLoSO..1281935B. doi:10.1371/journal.pone.0181935. PMC 5524406. PMID 28742125.
Black, M.L.; Wise, C.A.; Wang, W.; Bittles, A.H. (June 2006). "Combining Genetics and Population History in the Study of Ethnic Diversity in the People's Republic of China". Human Biology. 78 (3): 277–293. doi:10.1353/hub.2006.0041. PMID 17216801. S2CID 42002729.

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[vanOven2014-5] Van Oven M, Van Geystelen A, Kayser M, Decorte R, Larmuseau HD (2014). "Seeing the wood for the trees: a minimal reference phylogeny for the human Y chromosome". Human Mutation. 35 (2): 187–91. doi:10.1002/humu.22468. PMID 24166809. S2CID 23291764.

[ISOGG2015-6] International Society of Genetic Genealogy (ISOGG; 2015), Y-DNA Haplogroup Tree 2015. (Access date: 1 February 2015.)

[A0-T-7] Haplogroup A0-T is also known as A-L1085 (and previously as A0'1'2'3'4).

[A1-8] Haplogroup A1 is also known as A1'2'3'4.

[LT-9] Haplogroup LT (L298/P326) is also known as Haplogroup K1.

[K2-10] Between 2002 and 2008, Haplogroup T-M184 was known as "Haplogroup K2". That name has since been re-assigned to K-M526, the sibling of Haplogroup LT.

[K2a-11] Haplogroup K2a (M2308) and its primary subclade K-M2313 were separated from Haplogroup NO (F549) in 2016. (This followed the publication of: Poznik GD, Xue Y, Mendez FL, et al. (2016). "Punctuated bursts in human male demography inferred from 1,244 worldwide Y-chromosome sequences". Nature Genetics. 48 (6): 593–9. doi:10.1038/ng.3559. PMC 4884158. PMID 27111036. In the past, other haplogroups, including NO (M214) and K2e had also been identified with the name "K2a".

[K2b-12] Haplogroup K2b (M1221/P331/PF5911) is also known as Haplogroup MPS.

[K2e-13] Haplogroup K2e (K-M147) was previously known as "Haplogroup X" and "K2a" (but is a sibling subclade of the present K2a).

[K-M2313-14] K-M2313*, which as yet has no phylogenetic name, has been documented in two living individuals, who have ethnic ties to India and South East Asia. In addition, K-Y28299, which appears to be a primary branch of K-M2313, has been found in three living individuals from India. See: Poznik op. cit.; YFull YTree v5.08, 2017, "K-M2335", and; PhyloTree, 2017, "Details of the Y-SNP markers included in the minimal Y tree" (Access date of these pages: 9 December 2017)

[K2b1-15] Haplogroup K2b1 (P397/P399) is also known as Haplogroup MS, but has a broader and more complex internal structure.

[P-16] Haplogroup P (P295) is also klnown as K2b2.

[S-17] Haplogroup S, as of 2017, is also known as K2b1a. (Previously the name Haplogroup S was assigned to K2b1a4.)

[M-18] Haplogroup M, as of 2017, is also known as K2b1b. (Previously the name Haplogroup M was assigned to K2b1d.)

[1] Haber, Marc; Jones, Abigail L; Connell, Bruce A; Arciero, Elena; Yang, Huanming; Thomas, Mark G; Xue, Yali; Tyler-Smith, Chris (2019). "A Rare Deep-Rooting D0 African Y-Chromosomal Haplogroup and Its Implications for the Expansion of Modern Humans Out of Africa". Genetics. 212 (4): 1421–1428. doi:10.1534/genetics.119.302368. PMC 6707464. PMID 31196864.

[2] Underhill PA, Kivisild T (2007). "Use of Y chromosome and mitochondrial DNA population structure in tracing human migrations". Annu. Rev. Genet. 41: 539–64. doi:10.1146/annurev.genet.41.110306.130407. PMID 18076332.

[3] Brunelli, Andrea (July 24, 2017). "Y chromosomal evidence on the origin of northern Thai people". PLOS ONE. 12 (7): e0181935. Bibcode:2017PLoSO..1281935B. doi:10.1371/journal.pone.0181935. PMC 5524406. PMID 28742125.

[4] Black, M.L.; Wise, C.A.; Wang, W.; Bittles, A.H. (June 2006). "Combining Genetics and Population History in the Study of Ethnic Diversity in the People's Republic of China". Human Biology. 78 (3): 277–293. doi:10.1353/hub.2006.0041. PMID 17216801. S2CID 42002729.

Haplogroup CF

Distribution

See also

Genetics

Y-DNA C subclades

Y-DNA backbone tree

References