dNA polymerase III, delta subunit

In molecular biology, the δ (delta) subunit of DNA polymerase III is encoded by the holA gene in E. coli and other bacteria. Along with the γ, δ', χ, and ψ subunits that make up the core polymerase, and the β accessory proteins, the δ subunit is responsible for the high speed and processivity of polIII.[1][2]

DNA polymerase III, delta subunit
Identifiers
OrganismEscherichia coli
(str. K-12 substr. MG1655)
SymbolholA
Entrez947573
RefSeq (Prot)NP_415173.1
UniProtP28630
Other data
EC number2.7.7.7
Chromosomegenome: 0.67 - 0.67 Mb
Search for
StructuresSwiss-model
DomainsInterPro
DNA polymerase III, delta subunit
atpgs bound e. coli clamp loader complex
Identifiers
SymbolDNA_pol3_delta
PfamPF06144
Pfam clanCL0023
InterProIPR010372
SCOP21jql / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

References
  1. Dong Z, Onrust R, Skangalis M, O'Donnell M (June 1993). "DNA polymerase III accessory proteins. I. holA and holB encoding delta and delta'" (PDF). The Journal of Biological Chemistry. 268 (16): 11758–65. PMID 8505303.
  2. Carter JR, Franden MA, Aebersold R, McHenry CS (1992). "Molecular cloning, sequencing, and overexpression of the structural gene encoding the delta subunit of Escherichia coli DNA polymerase III holoenzyme". Journal of Bacteriology. 174 (21): 7013–25. doi:10.1128/jb.174.21.7013-7025.1992. PMC 207382. PMID 1400251.
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