Hydroxybutyrate-dimer hydrolase

The enzyme hydroxybutyrate-dimer hydrolase (EC 3.1.1.22) catalyzes the reaction

(R)-3-((R)-3-hydroxybutanoyloxy)butanoate + H2O 2 (R)-3-hydroxybutanoate
hydroxybutyrate-dimer hydrolase
Identifiers
EC no.3.1.1.22
CAS no.37278-37-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is (R)-3-((R)-3-hydroxybutanoyloxy)butanoate hydroxybutanoylhydrolase. The enzyme is also called D-(–)-3-hydroxybutyrate-dimer hydrolase. It participates in butanoate metabolism.

References

    • Delafield FP, Cooksey KE, Doudoroff M (1965). "β-Hydroxybutyric dehydrogenase and dimer hydrolase of Pseudomonas lemoignei". J. Biol. Chem. 240 (10): 4023–8. PMID 4954074.


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