Impromidine

Impromidine (INN) is a highly potent and specific histamine H2 receptor agonist.[1]

Impromidine
Clinical data
ATC code
  • none
Identifiers
  • 2-[3-(1H-imidazol-5-yl)propyl]-1-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H23N7S
Molar mass321.45 g·mol−1
3D model (JSmol)
  • Cc1[nH]cnc1CSCCNC(=N)NCCCc2c[nH]cn2
  • InChI=1S/C14H23N7S/c1-11-13(21-10-19-11)8-22-6-5-18-14(15)17-4-2-3-12-7-16-9-20-12/h7,9-10H,2-6,8H2,1H3,(H,16,20)(H,19,21)(H3,15,17,18) ☒N
  • Key:MURRAGMMNAYLNA-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

It has been used diagnostically as a gastric secretion indicator.

See also

References
  1. Durant G, Duncan W, Ganellin C, Parsons M, Blakemore R, Rasmussen A (1978). "Impromidine (SK&F 92676) is a very potent and specific agonist for histamine H2 receptors". Nature. 276 (5686): 403–5. doi:10.1038/276403a0. PMID 714166. S2CID 4242863.


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