List of PET radiotracers
This is a list of positron emission tomography (PET) radiotracers. These are chemical compounds in which one or more atoms have been replaced by a short-lived, positron emitting radioisotope.
Cardiology
Neurology
- [11C] 25B-NBOMe (Cimbi-36)
- [18F] Altanserin
- [11C] Carfentanil
- [11C] DASB
- [11C] DTBZ or [18F]Fluoropropyl-DTBZ
- [11C] [11C] ME@HAPTHI
- [18F] Fallypride
- [18F] Florbetaben
- [18F] Flubatine
- [18F] Fluspidine
- [18F] Florbetapir
- [18F] or [11C] Flumazenil
- [18F] Flutemetamol
- [18F] Fluorodopa
- [18F] Desmethoxyfallypride
- [18F] Mefway
- [18F] MPPF
- [18F] Nifene
- [11C] Pittsburgh compound B
- [11C] Raclopride
- [18F] Setoperone
- [18F] or [11C] N-Methylspiperone
- [11C] Verapamil
NIMH maintains a list of CNS radiotracers that may be useful for additional information.[1]
Neuroepigenetics
- [11C] Martinostat[2]
Oncology
- [18F] Fludeoxyglucose (18F) (FDG)-glucose analogue
- [11C] Acetate
- [11C] Methionine
- [11C] choline[3]
- [18F] EF5
- [18F] Fluciclovine[4]
- [18F] Fluorocholine
- [18F] FET
- [18F] FMISO
- [18F] Fluorothymidine F-18
- [64Cu] Cu-ETS2
- [64Cu] Copper-64 DOTA-TATE
- [68Ga] DOTA-pseudopeptides
- [68Ga] DOTA-TATE
- [68Ga] PSMA
- [68Ga] CXCR4; solid and hematologic cancers
Infectious diseases
- [18F] Fluorodeoxysorbitol (FDS)
References
- "CNS Radiotracer Table".
- Wey HY, Gilbert TM, Zürcher NR, She A, Bhanot A, Taillon BD, Schroeder FA, Wang C, Haggarty SJ, Hooker JM (10 August 2016). "Insights into neuroepigenetics through human histone deacetylase PET imaging". Science Translational Medicine. 8 (351): 351ra106. doi:10.1126/scitranslmed.aaf7551. PMC 5784409. PMID 27510902.
In neurological disorders, HDACs change expression in regions throughout the brain, but their dynamic contribution to human disease development over time is unknown. Wey et al. therefore developed and applied an HDAC imaging probe, called Martinostat, to visualize HDAC expression in the living brain. Martinostat was previously tested in rodents and nonhuman primates, and here, it is used for the first time in humans
- "Epigenetic Activity Imaged in Human Brain for First Time". Genetic Engineering & Biotechnology News. 11 August 2016.
- "Mayo Clinic Gets FDA Approval for New Imaging Agent for Recurrent Prostate Cancer". Mayo Clinic. November 8, 2012. Archived from the original on July 21, 2013.
- FDA approves new diagnostic imaging agent to detect recurrent prostate cancer
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