Luliconazole

Luliconazole, trade names Luzu among others, is an imidazole antifungal medication.[2] As a 1% topical cream, It is indicated for the treatment of athlete's foot, jock itch, and ringworm caused by dermatophytes such as Trichophyton rubrum, Microsporum gypseum[3] and Epidermophyton floccosum.[1]

Luliconazole
Clinical data
Trade namesLuzu, Luzarn, Lulicon, LULY, Zyluli,Luris
Routes of
administration		Topical
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Protein binding>99%[1]
Identifiers
  • (2E)-[(4R)-4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene](1H-imidazol-1-yl)acetonitrile
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H9Cl2N3S2
Molar mass354.27 g·mol−1
3D model (JSmol)
  • C1[C@H](S/C(=C(\C#N)/N2C=CN=C2)/S1)C3=C(C=C(C=C3)Cl)Cl
  • InChI=1S/C14H9Cl2N3S2/c15-9-1-2-10(11(16)5-9)13-7-20-14(21-13)12(6-17)19-4-3-18-8-19/h1-5,8,13H,7H2/b14-12+/t13-/m0/s1
  • Key:YTAOBBFIOAEMLL-REQDGWNSSA-N

References
  1. "LUZU (luliconazole) Cream, 1%. Full Prescribing Information" (PDF). Valeant Pharmaceuticals North America LLC. Retrieved 1 October 2015.
  2. Gupta AK, Daigle D (2016). "A critical appraisal of once-daily topical luliconazole for the treatment of superficial fungal infections". Infection and Drug Resistance. 9: 1–6. doi:10.2147/IDR.S61998. PMC 4723097. PMID 26848272.
  3. "FDA approves luliconazole for tinea pedis". November 19, 2013. Archived from the original on 16 January 2014. Retrieved 14 January 2014.


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