Tolciclate

Tolciclate (INN)[1]: 9  is an antifungal medication.[2][3]

Tolciclate
Space-filling model of the tolciclate molecule
Clinical data
Other namesO-(1,2,3,4-Tetrahydro-1,4-methanonaphthalen-6-yl) m,N-dimethylthiocarbanilate[1]
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • O-Tricyclo[6.2.1.02,7]undeca-2,4,6-trien-4-yl methyl(3-methylphenyl)carbamothioate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.051.611
Chemical and physical data
FormulaC20H21NOS
Molar mass323.45 g·mol−1
3D model (JSmol)
  • Cc1cccc(c1)N(C)C(=S)Oc2ccc3c(c2)C4CCC3C4
  • InChI=1S/C20H21NOS/c1-13-4-3-5-16(10-13)21(2)20(23)22-17-8-9-18-14-6-7-15(11-14)19(18)12-17/h3-5,8-10,12,14-15H,6-7,11H2,1-2H3 ☒N
  • Key:CANCCLAKQQHLNK-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

See also

References
  1. "International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary names: List 15" (PDF). World Health Organization. 1975. Retrieved 12 November 2016.
  2. Ryder NS, Frank I, Dupont MC (May 1986). "Ergosterol biosynthesis inhibition by the thiocarbamate antifungal agents tolnaftate and tolciclate". Antimicrobial Agents and Chemotherapy. 29 (5): 858–60. doi:10.1128/aac.29.5.858. PMC 284167. PMID 3524433.
  3. Bianchi A, Monti G, de Carneri I (September 1977). "Tolciclate: further antimycotic studies". Antimicrobial Agents and Chemotherapy. 12 (3): 429–30. doi:10.1128/aac.12.3.429. PMC 429931. PMID 907333.
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