Mannosylfructose-phosphate synthase

Mannosylfructose-phosphate synthase (EC 2.4.1.246, mannosylfructose-6-phosphate synthase, MFPS) is an enzyme with systematic name GDP-mannose:D-fructose-6-phosphate 2-alpha-D-mannosyltransferase.[1] This enzyme catalyses the following chemical reaction

GDP-mannose + D-fructose 6-phosphate GDP + beta-D-fructofuranosyl-alpha-D-mannopyranoside 6F-phosphate
Mannosylfructose-phosphate synthase
Identifiers
EC no.2.4.1.246
CAS no.92480-04-1 (not distinguished from EC 2.4.1.167)
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

This enzyme, from the soil proteobacterium and plant pathogen Agrobacterium tumefaciens strain C58, requires Mg2+ or Mn2+ for activity.

References

  1. Torres LL, Salerno GL (September 2007). "A metabolic pathway leading to mannosylfructose biosynthesis in Agrobacterium tumefaciens uncovers a family of mannosyltransferases". Proceedings of the National Academy of Sciences of the United States of America. 104 (36): 14318–23. doi:10.1073/pnas.0706709104. PMC 1964871. PMID 17728402.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.