Mannosylglycerate synthase

Mannosylglycerate synthase (EC 2.4.1.269) is an enzyme with systematic name GDP-mannose:D-glycerate 2-alpha-D-mannosyltransferase.[1][2] This enzyme catalyses the following chemical reaction

GDP-mannose + D-glycerate GDP + 2-O-(alpha-D-mannopyranosyl)-D-glycerate
Mannosylglycerate synthase
Identifiers
EC no.2.4.1.269
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

Depending on conditions mannosylglycerate synthase is more or less specific for the GDP-mannose and D-glycerate.

See also

References

  1. Martins LO, Empadinhas N, Marugg JD, Miguel C, Ferreira C, da Costa MS, Santos H (December 1999). "Biosynthesis of mannosylglycerate in the thermophilic bacterium Rhodothermus marinus. Biochemical and genetic characterization of a mannosylglycerate synthase". The Journal of Biological Chemistry. 274 (50): 35407–14. doi:10.1074/jbc.274.50.35407. PMID 10585410.
  2. Flint J, Taylor E, Yang M, Bolam DN, Tailford LE, Martinez-Fleites C, Dodson EJ, Davis BG, Gilbert HJ, Davies GJ (July 2005). "Structural dissection and high-throughput screening of mannosylglycerate synthase". Nature Structural & Molecular Biology. 12 (7): 608–14. doi:10.1038/nsmb950. PMID 15951819.
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