N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase

In enzymology, a N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase (EC 2.4.1.188) is an enzyme that catalyzes the chemical reaction

UDP-glucose + N-acetyl-D-glucosaminyldiphosphoundecaprenol UDP + beta-D-glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol
N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase
Identifiers
EC no.2.4.1.188
CAS no.118731-83-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

Thus, the two substrates of this enzyme are UDP-glucose and N-acetyl-D-glucosaminyldiphosphoundecaprenol, whereas its two products are UDP and beta-D-glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:N-acetyl-D-glucosaminyldiphosphoundecaprenol 4-beta-D-glucosyltransferase. Other names in common use include UDP-D-glucose:N-acetylglucosaminyl pyrophosphorylundecaprenol, glucosyltransferase, uridine, diphosphoglucose-acetylglucosaminylpyrophosphorylundecaprenol, and glucosyltransferase.

References

    • Kumita K, Murazumi N, Araki Y, Ito E (December 1988). "Solubilization and properties of UDP-D-glucose:N-acetylglucosaminyl pyrophosphorylundecaprenol glucosyltransferase from Bacillus coagulans AHU 1366 membranes". J. Biochem. Tokyo. 104 (6): 985–8. PMID 2977388.


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