Acetylgalactosaminyl-O-glycosyl-glycoprotein b-1,3-N-acetylglucosaminyltransferase
Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase (EC 2.4.1.147, O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III, uridine diphosphoacetylglucosamine-mucin beta(1->3)-acetylglucosaminyltransferase, mucin core 3 beta3-GlcNAc-transferase, Core 3beta-GlcNAc-transferase, UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosaminyl-R) beta-1,3-N-acetyl-D-glucosaminyltransferase) is an enzyme with systematic name UDP-N-acetyl-D-glucosamine:N-acetyl-beta-D-galactosaminyl-R 3-beta-N-acetyl-D-glucosaminyltransferase.[1] This enzyme catalyses the following chemical reaction
- UDP-N-acetyl-D-glucosamine + N-acetyl-beta-D-galactosaminyl-R UDP + N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
| Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.4.1.147 | ||||||||
| CAS no. | 87927-96-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
See also
- EC 2.4.1.102 (beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase)
- EC 2.4.1.146 (beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase)
- EC 2.4.1.148 (acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase).
References
- Brockhausen I, Rachaman ES, Matta KL, Schachter H (August 1983). "The separation by liquid chromatography (under elevated pressure) of phenyl, benzyl, and O-nitrophenyl glycosides of oligosaccharides. Analysis of substrates and products for four N-acetyl-D-glucosaminyl-transferases involved in mucin synthesis". Carbohydrate Research. 120: 3–16. doi:10.1016/0008-6215(83)88002-1. PMID 6226356.
External links
- Acetylgalactosaminyl-O-glycosyl-glycoprotein+beta-1,3-N-acetylglucosaminyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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