Parkeol synthase

Parkeol synthase (EC 5.4.99.47) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, parkeol-forming).[1] This enzyme catalyses the following chemical reaction

(3S)-2,3-epoxy-2,3-dihydrosqualene parkeol
Parkeol synthase
Identifiers
EC no.5.4.99.47
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

The enzyme from rice (Oryza sativa) produces only parkeol.

References

  1. Ito R, Mori K, Hashimoto I, Nakano C, Sato T, Hoshino T (May 2011). "Triterpene cyclases from Oryza sativa L.: cycloartenol, parkeol and achilleol B synthases". Organic Letters. 13 (10): 2678–81. doi:10.1021/ol200777d. PMID 21526825.
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