Poly(ribitol-phosphate) N-acetylglucosaminyl-transferase

In enzymology, a poly(ribitol-phosphate) N-acetylglucosaminyl-transferase (EC 2.4.1.70) is an enzyme that catalyzes the chemical reaction

UDP-N-acetyl-D-glucosamine + poly(ribitol phosphate) UDP + (N-acetyl-D-glucosaminyl)poly(ribitol phosphate)
poly(ribitol-phosphate) N-acetylglucosaminyltransferase
Identifiers
EC no.2.4.1.70
CAS no.37277-71-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

Thus, the two substrates of this enzyme are UDP-N-acetyl-D-glucosamine and poly(ribitol phosphate), whereas its two products are UDP and (N-acetyl-D-glucosaminyl)poly(ribitol phosphate).

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-N-acetyl-D-glucosamine:poly(ribitol-phosphate) N-acetyl-D-glucosaminyltransferase. Other names in common use include UDP acetylglucosamine-poly(ribitol phosphate), acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-poly(ribitol phosphate), and acetylglucosaminyltransferase.

References

    • Nathenson SG, Ishimoto N, Strominger JL (1966). "UDP-N-acetylglucosamine:polyribitol phosphate N-acetylglucosaminyltransferases from Staphylococcus aureus". Methods Enzymol. Methods in Enzymology. 8: 426–429. doi:10.1016/0076-6879(66)08079-0. ISBN 978-0-12-181808-1.


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