Ribonuclease U2

Ribonuclease U2 (EC 3.1.27.4, purine specific endoribonuclease, ribonuclease U3, RNase U3, RNase U2, purine-specific ribonuclease, purine-specific RNase, Pleospora RNase, Trichoderma koningi RNase III, ribonuclease (purine)) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction

Two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Ap or Gp with 2',3'-cyclic phosphate intermediates
Ribonuclease U2
Identifiers
EC no.3.1.27.4
CAS no.37205-57-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

References

  1. Glitz DG, Dekker CA (October 1964). "Studies on a ribonuclease from Ustilago sphaerogena. I. Purification and properties of the enzyme". Biochemistry. 3 (10): 1391–9. doi:10.1021/bi00898a001. PMID 14230791.
  2. Glitz DG, Dekker CA (October 1964). "Studies on a ribonuclease from Ustilago sphaerogena. II. Specificity of the enzyme". Biochemistry. 3 (10): 1399–406. doi:10.1021/bi00898a002. PMID 14230792.
  3. Uchida T, Egami F (1971). "Microbial ribonucleases with special reference to RNases T1, T 2, N 1, and U2". In Boyer PD (ed.). The Enzymes. Vol. 4 (3rd ed.). New York: Academic Press. pp. 205–250.
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