Mitochondrial thiamine pyrophosphate carrier
Mitochondrial thiamine pyrophosphate carrier is a protein that in humans is encoded by the SLC25A19 gene.[5][6][7]
| SLC25A19 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | SLC25A19, DNC, MCPHA, MUP1, THMD3, THMD4, TPC, solute carrier family 25 member 19 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 606521 MGI: 1914533 HomoloGene: 5982 GeneCards: SLC25A19 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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See also
References
- GRCh38: Ensembl release 89: ENSG00000125454 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000020744 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- Iacobazzi V, Ventura M, Fiermonte G, Prezioso G, Rocchi M, Palmieri F (Jul 2001). "Genomic organization and mapping of the gene (SLC25A19) encoding the human mitochondrial deoxynucleotide carrier (DNC)". Cytogenet Cell Genet. 93 (1–2): 40–2. doi:10.1159/000056945. PMID 11474176. S2CID 44985945.
- Dolce V, Fiermonte G, Runswick MJ, Palmieri F, Walker JE (Mar 2001). "The human mitochondrial deoxynucleotide carrier and its role in the toxicity of nucleoside antivirals". Proc Natl Acad Sci U S A. 98 (5): 2284–8. Bibcode:2001PNAS...98.2284D. doi:10.1073/pnas.031430998. PMC 30130. PMID 11226231.
- "Entrez Gene: SLC25A19 solute carrier family 25 (mitochondrial deoxynucleotide carrier), member 19".
Further reading
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Rosenberg MJ, Agarwala R, Bouffard G, et al. (2002). "Mutant deoxynucleotide carrier is associated with congenital microcephaly". Nat. Genet. 32 (1): 175–9. doi:10.1038/ng948. PMID 12185364. S2CID 23768596.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Carrisi C, Antonucci D, et al. (2013). "Transport of platinum bonded nucleotides into proteoliposomes, mediated by Drosophila melanogaster thiamine pyrophosphate carrier protein (DmTpc1)". Journal of Inorganic Biochemistry. 130: 28–31. doi:10.1016/j.jinorgbio.2013.09.012. PMID 24148759.
- Lam W, Chen C, Ruan S, et al. (2005). "Expression of deoxynucleotide carrier is not associated with the mitochondrial DNA depletion caused by anti-HIV dideoxynucleoside analogs and mitochondrial dNTP uptake". Mol. Pharmacol. 67 (2): 408–16. doi:10.1124/mol.104.007120. PMID 15539640. S2CID 25269301.
- Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
- Lindhurst MJ, Fiermonte G, Song S, et al. (2006). "Knockout of Slc25a19 causes mitochondrial thiamine pyrophosphate depletion, embryonic lethality, CNS malformations, and anemia". Proc. Natl. Acad. Sci. U.S.A. 103 (43): 15927–32. Bibcode:2006PNAS..10315927L. doi:10.1073/pnas.0607661103. PMC 1595310. PMID 17035501.
- Iacopetta D, Carrisi C, et al. (2010). "The biochemical properties of the mitochondrial thiamine pyrophosphate carrier from Drosophila melanogaster". FEBS J. 277 (5): 1172–81. doi:10.1111/j.1742-4658.2009.07550.x. PMID 20121944. S2CID 24140143.
External links
- GeneReviews/NCBI/NIH/UW entry on Amish Lethal Microcephaly
- OMIM entries on Amish Lethal Microcephaly
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