WNT2

Wingless-type MMTV integration site family, member 2, also known as WNT2, is a human gene.[5][6]

WNT2
Identifiers
AliasesWNT2, INT1L1, IRP, Wnt family member 2
External IDsOMIM: 147870 MGI: 98954 HomoloGene: 20719 GeneCards: WNT2
Orthologs
SpeciesHumanMouse
Entrez

7472

22413

Ensembl

ENSG00000105989

ENSMUSG00000010797

UniProt

P09544

P21552

RefSeq (mRNA)

NM_003391

NM_023653

RefSeq (protein)

NP_003382

NP_076142

Location (UCSC)Chr 7: 117.28 – 117.32 MbChr 6: 17.99 – 18.03 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene is a member of the WNT gene family. The WNT gene family consists of structurally related genes that encode secreted signaling proteins involved in the Wnt signaling pathway. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Alternatively spliced transcript variants have been identified for this gene.[5]

References

  1. GRCh38: Ensembl release 89: ENSG00000105989 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000010797 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: WNT2 wingless-type MMTV integration site family, member 2".
  6. Wainwright BJ, Scambler PJ, Stanier P, Watson EK, Bell G, Wicking C, Estivill X, Courtney M, Boue A, Pedersen PS (June 1988). "Isolation of a human gene with protein sequence similarity to human and murine int-1 and the Drosophila segment polarity mutant wingless". EMBO J. 7 (6): 1743–8. doi:10.1002/j.1460-2075.1988.tb03003.x. PMC 457162. PMID 2971536.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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