Zinc finger protein 180

ZNF180
Identifiers
Aliases	ZNF180, HHZ168, zinc finger protein 180
External IDs	OMIM: 606740 MGI: 1923701 HomoloGene: 8306 GeneCards: ZNF180
Gene location (Human)
Chr.	Chromosome 19 (human)[1]
End	44,500,524 bp[1]
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)[2]
End	23,807,138 bp[2]
RNA expression pattern
	Top expressed in
	endothelial cell; ; Achilles tendon; ; ganglionic eminence; ; islet of Langerhans; ; sural nerve; ; parietal pleura; ; monocyte; ; stromal cell of endometrium; ; rectum; ; left adrenal gland;
	Top expressed in
	hand; ; olfactory tubercle; ; superior cervical ganglion; ; primary motor cortex; ; Region I of hippocampus proper; ; superior frontal gyrus; ; nucleus accumbens; ; cingulate gyrus; ; globus pallidus; ; otolith organ;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; protein binding; metal ion binding; nucleic acid binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	intracellular anatomical structure; nucleus;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	7733
	210135
	ENSG00000167384
	ENSMUSG00000057101
	Q9UJW8
	n/a
NM_001278508; NM_001278509; NM_001288759; NM_001288760; NM_001288761;
	NM_001288762; NM_001291633; NM_013256
NM_001045486; NM_001289634; NM_001289637; NM_001289640; NM_001289641;
	NM_172483
NP_001265437; NP_001265438; NP_001275688; NP_001275689; NP_001275690;
	NP_001275691; NP_001278562; NP_037388
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger protein 180 is a protein that is encoded in humans by the ZNF180 gene. [5]

Function

Zinc finger proteins have been shown to interact with nucleic acids and to have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing two specifically positioned cysteines and two histidines that are involved in coordinating zinc. Kruppel-related proteins form one family of zinc finger proteins. See MIM 604749 for additional information on zinc finger proteins.

References

GRCh38: Ensembl release 89: ENSG00000167384 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000057101 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Zinc finger protein 180". Retrieved 2016-01-29.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000167384 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000057101 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Zinc finger protein 180". Retrieved 2016-01-29.