Copper gluconate

Copper gluconate is the copper salt of D-gluconic acid. It is an odorless light blue or blue-green crystal or powder which is easily soluble in water and insoluble in ethanol.[1][2]

Copper gluconate
Clinical data
AHFS/Drugs.comMicromedex Detailed Consumer Information
MedlinePlusa601072
Routes of
administration		Oral
ATC code
Identifiers
IUPAC name
  • Copper(II) gluconate
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.007.645
Chemical and physical data
FormulaC12H22CuO14
Molar mass453.8 g·mol−1
3D model (JSmol)
Melting point156 °C (313 °F)
Solubility in water30 mg/mL (20 °C)
SMILES
  • C([C@H]([C@H]([C@@H]([C@H](C(=O)[O-])O)O)O)O)O.C([C@H]([C@H]([C@@H]([C@H](C(=O)[O-])O)O)O)O)O.[Cu+2]
InChI
  • InChI=1S/2C6H12O7.Cu/c2*7-1-2(8)3(9)4(10)5(11)6(12)13;/h2*2-5,7-11H,1H2,(H,12,13);/q;;+2/p-2/t2*2-,3-,4+,5-;/m11./s1 N
  • Key:OCUCCJIRFHNWBP-IYEMJOQQSA-L N
 NY (what is this?)  (verify)

Uses

Side effects

The U.S. Institute of Medicine (IOM) sets Tolerable upper intake levels (ULs) for vitamins and minerals when evidence is sufficient. In the case of copper the adult UL is set at 10 mg/day.[4]

Copper gluconate is sold as a dietary supplement to provide copper. The typical dose is 2.0 mg copper per day. This is one-fifth what the IOM considers a safe upper limit. Long-term intake at amounts higher than the UL may cause liver damage.[4]

References
  1. "产品列表-葡萄糖酸铜" [Product list - copper gluconate]. Liaoyang Tengyuan Food Additives Factory. Archived from the original on April 2, 2015. Retrieved March 29, 2013. (in Chinese)
  2. "Copper Gluconate". ChemicalLand21. Retrieved March 29, 2013.
  3. Sawyer DT (1964). "Metal-Gluconate Complexes". Chemical Reviews. 64 (6): 633–643. doi:10.1021/cr60232a003.
  4. Food and Nutrition Board, Institute of Medicine (2001). "Chapter 9: Copper". DRI: dietary reference intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc : a report of the Panel on Micronutrients ... and the Standing Committee on the Scientific Evaluation of Dietary Reference Intakes. Washington, D.C.: National Academy Press. pp. 224–257. ISBN 978-0-309-07290-8.


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